Summary

doi: 10.25005/2074-0581-2012-14-1-47-53
Influence of climatic conditions on the formation of pathological scar of skin

K.M. Mukhamadieva, O.B. Nemchaninova, K.P. Artykov, M.S. Saidov

In 194 patients with a pathological skin scarring, living in different regions of Tajikistan, conducted a study of immunological parameters of blood, the state of lipid peroxidation (LPO) and antioxidant protection (AOp), as well as electric thermometer and the impedance in the area of scarring. Comparison of immune parameters in these patients revealed that the most pronounced changes are observed in patients with keloid scars, living in lowland areas and in midlands. In patients with scarring of the skin, living in conditions of highmountain, significant changes in the immune system were observed. The highest frequency of keloid and hypertrophic scars in people living in lowland areas may be associated with changes in their immune parameters and activation processes of free radical oxidation, which affects the local tissue reactions in the skin scars which the inhabitants of the valley differ fever and decrease the ohmic resistance of the tissues.

Keywords: keloid scars, immunological parameters, lipid peroxidation, antioxidant protection, climatic factors, electric thermometer, impedancemetry.

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