Effectiveness of controlled therapy of arterial hypertension in persons of middle age

G.M. Negmatova, G.A. Acheva, Kh.Yo. Sharipova, R.G. Sohibov

Chair of Propaedeutics of Internal Medicine Avicenna TSMU

The results of the comparative assessment the effectiveness of mild and moderate arterial hypertension (AH) therapy in 117 middle-aged men receiving the traditional (group 1) and controlled (group 2) therapy were shown in article.

It was found that as on background of traditional therapy and controlled hypertension at hospital discharge, compared with initial data, there was a significant increase in proportion of confined to treatment, reducing the average levels of systolic and diastolic blood pressure, increase in the frequency of optimal blood pressure profile. However, according to a prospective study, the therapeutic effect of controlled treatment of mild and moderate hypertension in middle-aged men is preserved much longer than the traditional one.

In group 1 patients proportion of confined to treatment during the observation gradually decreased (<0,05), SBP and DBP levels at the end of observation were higher than those at discharge (<0,05), decreased the frequency of optimal daily blood pressure profile. In 2 patients, despite a slight decrease in confined to treatment, increase the levels of systolic and diastolic blood pressure, decrease the optimaldaily BP profile, their values at discharge and at the end of the observation did not differ significantly (>0,05). A statistically significant reduction in the incidence of inadequate nocturnal SBP reduction (p<0,001) found only at a controlled therapy.

Keywords: arterial hypertension, confined to treatment.

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