Antibiotic-resistant gram-positive microflora isolated from metro aspirates in parturients with postpartum endometritis

N.A. Korobkov

Chair of reproductive health of women Northwestern State Medical University named after II Mechnikov, Saint-Petersburg, Russia

A microbiological examination of lochia in 130 postpartum women with postpartum endometritis in order to determine the etiological structure and antibiotic resistance of most clinically significant aerobic flora. Material for the study was metroaspirat (130 samples). The most frequently (86,2%) were inoculated microorganisms in the form of associations and mostly observed aerobic-anaerobic (55,4%).

In the structure of selected aerobic microflora prevailed (61,7%), gram-positive aerobic coccal flora (Enterococcus spp. - 43,2% and S. aureus - 15,3%). The main identified problems were high antibiotic resistance of enterococci to aminoglycosides isolated (47,1%) and methicillin resistance in S. aureus.

Based on these results obtained in theresearch hospital, recommendations on changing approaches to empirical treatment of post-partum infections were proposed. The only drug that was active against all tested strains, including multidrug-resistant Enterococcus spp. and MRSA, was glycopeptide antibiotic vancomycin, which should be recommended for empirical treatment of severe postpartum infections in this maternity hospital.

Keywords: postpartum endometritis, metroaspirat, lochia, antibiotic resistance of Gram-positive microflora resistance of enterococci to aminoglycosides, MRSA.

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