Summary

doi: 10.25005/2074-0581-2014-16-4-84-89
Diagnostic value of homocysteine and lipid metabolism indicies in patients at early recovery period of ischemic stroke

T.V. Mironenko, L.V. Yakovleva

SI «Lugansk State Medical University»
Chair of Nervous Diseases with Neurosurgery, Lugansk, Ukraine

The analysis of the diagnostic value of plasma homocysteine and lipoprotein cholesterol fractions on neurological disorders dynamics at early recovery period of ischemic stroke presented in article.

Were examined 70 patients suffered from ischemic stroke with 1-4 months prescriptions, and 20 patients of control group - with atherosclerotic encephalopathy II stage.

The data of the study show the structure of identified neurological symptoms prevailed autonomic dysfunction, along with focal neurological deficit. In all patients, there was an increase in the blood levels of total cholesterol, LDL cholesterol and very low density, triglycerides, atherogenic index, homocysteine compared with the control group (p <0,001).

At early recovery period of ischemic stroke increase in blood levels of total cholesterol, LDL and very low density, triglycerides, atherogenic index, which is combined with an increase in plasma homocysteine is determined.

A direct correlation between the atherogenic index of blood and plasma homocysteine levels; homocysteine blood levels and low density lipoprotein cholesterol is established that have certain diagnostic and, perhaps, prognostic significance.

Keywords: ischemic stroke, atherosclerotic encephalopathy, homocysteine, lipid metabolism, vegetative dysfunction.

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