Summary

doi: 10.25005/2074-0581-2009-11-3-84-90
ALTERATIONS OF INDEXES OF LOCAL IMMUNITY OF MAXILLA-SINUS UNDER THERAPY OF PATIENTS WITH CHRONIC PURULENT RINOSINUSITIS BY PREPARATE RECOMBINANT INTERLEUKIN-1 BETA (BETALEUKIN)

Z.S. Gulomov, E.A. Varyushina, Yu.K. Yanov, A.S. Simbircev

In the article immunestimulating effect of betaleukin is analysed. The preparate finds clinical use under immune-deficit state accompaning some time serious complications and demanding urgent effective immune-replaced therapy. The preparate was used under chronic purulent rinosinusitis locally. The irrigation of sinus by antiseptic solutions, medicines dioxidin and betaleukin was made by punction or sinus-cateter. The results show high clinical immune effect of local immune corrigirung therapy by betaleukin under one- and twoside pathology. The best clinical result under the use of betaleukin was received in patients with one side-process.

Keywords: chronic purulent rinosinusitis , interleukin-1 beta, immunity.

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