REVIEW ARTICLE
General Surgery
doi: 10.25005/2074-0581-2025-27-4-976-985
OPTIMIZED PERIOPERATIVE MANAGEMENT (FAST-TRACK, ERAS) TO ENHANCE POSTOPERATIVE RECOVERY IN PANCREATICODUODENECTOMY

D.A. ABDULLOZODA1, YU.F. TAGOYMURODOV1, S.G. ALI-ZADE2

1Department of General Surgery No. 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
2Department of Surgical Diseases No. 1 named after Academician K.M. Kurbonov, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan

Pancreaticoduodenectomy (PD) is one of the most complex surgeries in abdominal surgery, associated with a high risk of postoperative complications and prolonged hospital stays. The concept of Enhanced Recovery After Surgery (ERAS) provides a multimodal approach to perioperative patient management, aiming to reduce surgical stress and accelerate rehabilitation.

This review was conducted following the principles of a systematic literature review. We searched for publications from 2014 to 2024 in the PubMed, Scopus, and eLibrary databases using the keywords "ERAS", "pancreaticoduodenectomy", "enhanced recovery", and "fast-track". We included original articles, meta-analyses, and clinical guidelines; clinical cases and non-peer-reviewed publications were excluded. The application of ERAS protocols in PD has been shown to reduce the incidence of complications, shorten hospital stays, and lower financial costs without increasing mortality risk. Key components of the ERAS protocol include early enteral nutrition, multimodal analgesia, early mobilization, and optimized fluid management and prophylaxis of thromboembolism and infections. Despite its proven effectiveness, the successful implementation of ERAS requires a multidisciplinary approach and tailoring to each patient's characteristics. Future research should focus on refining the optimal components of the protocol, identifying risk factors for ERAS failure, and developing personalized patient management strategies after PD. Additionally, studying long-term outcomes, including post-surgery quality of life, is an important area for further investigation.

Keywords: Pancreaticoduodenectomy, accelerated recovery, ERAS, fast-track surgery, postoperative complications.

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References
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Authors' information:

Abdullozoda Dzhamoliddin Abdullo,
Doctor of Medical Sciences, Full Professor, Professor of the Department of General Surgery No. 2, Avicenna Tajik State Medical University
ORCID ID: 0000-0002-2910-1441
SPIN: 9268-0866
Author ID: 960954
E-mail: abdullozoda-jamoliddin@mail.ru

Tagoymurodov Yusuf Fayzovich,
Postgraduate Student of the Department of General Surgery No. 2, Avicenna Tajik State Medical University
ORCID ID: 0009-0001-5666-4821
SPIN: 8683-3746
Author ID: 1286437
E-mail: yusuf.tagoymurodov@gmail.com

Ali-Zade Sukhrob Gaffarovich,
Candidate of Medical Sciences, Associate Professor of the Department of Surgical Diseases No. 1 named after Academician K.M. Kurbonov, Avicenna Tajik State Medical University
ORCID ID: 0000-0002-2456-7509
SPIN: 6854-5343
Author ID: 258253
E-mail: suhrob_a@mail.ru

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Ali-Zade Sukhrob Gaffarovich
Candidate of Medical Sciences, Associate Professor of the Department of Surgical Diseases No. 1 named after Academician K.M. Kurbonov, Avicenna Tajik State Medical University

734026, Republic of Tajikistan, Dushanbe, Sino str., 29-31

Tel.: +992 (928) 217755

E-mail: suhrob_a@mail.ru


This work is licensed under a Creative Commons Attribution 4.0 International License.

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