General Surgery
doi: 10.25005/2074-0581-2026-28-1-100-111
COMPARISON OF THE CLINICAL EFFICACY OF DIFFERENT ABDOMINAL WALL HERNIOPLASTY METHODS USING STANDARD VERSUS NAFION-COATED MESH PROSTHESES
1Kabardino-Balkarian State University named after Kh.M. Berbekov, Nalchik, Russian Federation
2Kadyrov Chechen State University, Grozny, Russian Federation
3Levshin Institute of Cluster Oncology, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation
Objective: The study aimed to evaluate the clinical effectiveness of on-lay hernioplasty and anterior component separation using traditional endoprostheses versus Nafion-coated endoprostheses.
Methods: A prospective, non-randomized study was conducted on 140 patients divided into two groups. The study group (n=60) underwent repair using a polypropylene endoprosthesis with a Nafion coating. The control group (n=80) received a traditional endoprosthesis. Groups were further divided into subgroups based on the surgical technique: Subgroups 1A (n=25) and 2A (n=35) underwent on-lay repair, while Subgroups 1B (n=40) and 2B (n=40) underwent anterior separation hernioplasty. All patients underwent standard examinations with a 6-month follow-up. The incidence, nature, and timing of suppurative complications, inflammatory infiltrates, and the volume of lymphorrhea were recorded. Statistical analysis was performed using SPSS 17.0 (IBM Corp., Armonk, NY, USA).
Results: For hernia defects up to 5 cm, the use of Nafion-coated endoprostheses yielded results identical to traditional meshes, regardless of the repair method. However, for defects between 5 cm and 15 cm, significant differences were noted. The Nafion-coated group showed negative wound cultures for pathogenic microflora. Furthermore, separation repairs using the Nafion-coated mesh resulted in significantly lower rates of purulent complications, infiltrates, and seromas compared to the control group.
Conclusion: The use of Nafion-coated polypropylene endoprostheses in various types of anterior abdominal wall repair for PVH patients led to a significant reduction in postoperative lymphorrhea and purulent-inflammatory complications.
Keywords: Postoperative ventral hernia, separation hernioplasty, Nafion, wound suppuration, seroma, polypropylene endoprosthesis.
References
- Romashchenko PN, Kurygin AA, Semyonov VV, Prudieva SA. Sotsial'no- ekonomicheskie aspekty lecheniya bol'nykh srednimi (W2) i bol'shimi (W3) posleoperatsionnymi ventral'nymi gryzhami [Socio-economic aspects of treatment of patients with medium (W2) and large (W3) postoperative ventral hernias]. Vestnik khirurgii imeni I.I. Grekova. 2022;181(4):29-35. https://doi. org/10.24884/0042-4625-2022-181-4-29-35
- Abalyan AK, Aydemirov AN, Vafin AZ, Mashurova EV, Aidemirova EA. Nash opyt lecheniya posleoperatsionnykh ventral'nykh gryzh [Our experience of treatment of incisional ventral hernias]. Meditsinskiy vestnik Severnogo Kavkaza. 2019;14(1.1):19-21. https://doi.org/10.14300/mnnc.2019.14039
- Hartog F, Sneiders D, Darwish EF, Yurtkap Y, Menon AG, Muysoms FE, et al. Favorable outcomes after Retro-Rectus (Rives-Stoppa) mesh repair as treatment for noncomplex ventral abdominal wall hernia, a systematic review and meta-analysis. Ann Surg. 2022;276(1):55-65. https://doi.org/10.1097/ SLA.0000000000005422
- Tryliskyy Y, Demykhova I, Kebkalo A, Pournaras DJ. Minimally invasive extended totally extraperitoneal versus transabdominal retromuscular ventral hernia mesh repair: Systematic review and meta-analysis. J Laparoendosc Adv Surg Tech A. 2024;34(1):39-46. https://doi.org/10.1089/lap.2023.0342
- Henriksen NA, Bougard H, Gonçalves MR, Hope W, Khare R, Shao J, et al. Primary ventral and incisional hernias: Comprehensive review. BJS Open. 2024;9(1):145. https://doi.org/10.1093/bjsopen/zrae145
- Elhadidi A, Shetiwy M, Al-Katary M. Comparative analysis of laparoscopic, retro- muscular, and open mesh repair techniques for ventral and incisional hernias: A comprehensive review and meta-analysis. Updates Surg. 2025;77(1):217-29. https://doi.org/10.1007/s13304-024-02049-1
- Miserez M, Jairam AP, Boersema GSA, Bayon Y, Jeekel J, Lange JF. Resorbable synthetic meshes for abdominal wall defects in preclinical setting: A literature review. J Surg Res. 2019;237:67-75. https://doi.org/10.1016/j.jss.2018.11.054
- Sahoo S, Haskins IN, Huang LC, Krpata DM, Derwin KA, Poulose BK, et al. Early wound morbidity after open ventral hernia repair with biosynthetic or polypropylene mesh. J Am Coll Surg. 2017;225:472-80. https://doi.org/10.1016/j. jamcollsurg.2017.07.1067
- Lubyansky VG, Seroshtanov VV, Leontiev SV, Shtyrov DM. Podkovyrov SA. Primenenie original'nogo fibrinovogo pokrytiya v proteziruyushchey gernioplastike u bol'nykh s posleoperatsionnymi ventral'nymi gryzhami [The use of an original fibrin coating in prosthetic hernioplasty in patients with postoperative ventral hernias]. Acta Biomedical Scientifica. 2025;10(2):202-8. https://doi.org/10.29413/ABS.2025-10.2.20
- Fernandez-Moure JS, Van Eps JL, Scherba JC, Yazdi IK, Robbins A, Cabrera F, et al. Platelet-rich plasma enhances mechanical strength of strattice in rat model of ventral hernia repair. J Tissue Eng Regen Med. 2021;15(7):634-7. https://doi. org/10.1002/term.3200
- Okonkwo PC, Ben Belgacem I, Emori W, Uzoma PC. Nafion degradation mechanisms in proton exchange membrane fuel cell (PEMFC) system: A review. International Journal of Hydrogen Energy. 2021;46(55):27956-73. https://doi.org/10.1016/j.ijhydene.2021.06.032
- Ninham BW, Battye MJ, Bolotskova PN, Gerasimov RY, Kozlov VA, Bunkin NF. Nafion: New and old insights into structure and function. Polymers (Ba- sel).2023;15(9):2214. https://doi.org/10.3390/polym15092214
- Bunkin NF, Bolotskova PN, Gudkov SV, Khuong MT, Kozlov VA, Timchenko SL, et al. Nafion: A flexible template for selective structuring. Polymers (Ba- sel).2024;16(6):744. https://doi.org/10.3390/polym16060744
- Kelarakis A. Nafion in biomedicine and healthcare. Polymers. 2025;17(15):2054. https://doi.org/10.3390/polym17152054
- Tang G, Zhao C, Zhao X, Mei D, Pan, Y, Li B, et al. Nafion/polyimide based programmable moisture-driven actuators for functional structures and robots. Sens Actuators B Chem. 2023;393:134152. https://doi.org/10.1016/j. snb.2023.134152 393
- Turner RF, Harrison DJ, Rajotte RV. Preliminary in vivo biocompatibility studies on perfluorosulphonic acid polymer membranes for biosensor applications. Bioma- terials. 1991;12(4):361-8. https://doi.org/10.1016/0142-9612(91)90003-s
- Egiev VN, Lyadov VK, Bogomazova SYu. Sravnitel'naya otsenka materialov dlya vnutribryushinnoy plastiki ventral'nykh gryzh: eksperimental'noe issledovanie [Intraperitoneal ventral hernia plasty: The comparison of prosthetic materials]. Khirurgiya. Zhurnal im. N.I. Pirogova. 2010;10:36‑41.
Authors' information:
Vaganov Aleksey Gennadievich,
Candidate of Medical Sciences, Associate Professor of the Department of Hospital Surgery, Kabardino-Balkarian State University named after Kh.M. Berbekov; Associate Professor of the Department of International Medical Education, Kadyrov Chechen State University
ORCID ID: 0000-0001-8191-2551
SPIN: 2202-0746
Author ID: 1243342
E-mail: aleksejvaganov4@gmail.com
Aslanov Akhmed Dzonovich,
Doctor of Medical Sciences, Full Professor, Head of the Department of Hospital Surgery, Kabardino-Balkarian State University named after Kh.M. Berbekov
ORCID ID: 0000-0002-7051-0917
SPIN code: 1452-7020
Author ID: 263474
E-mail: dr.aslanov1967@mail.ru
Kuznetsov Maksim Robertovich,
Doctor of Medical Sciences, Full Professor, Deputy Director of the Levshin Institute of Cluster Oncology, I.M. Sechenov First Moscow State Medical University
ORCID ID: 0000-0001-6926-6809
SPIN: 7146-1348
Author ID: 151399
E-mail: mrkuznetsov@mail.ru
Shono Arsbi Ahmad,
Head of the Department of International Education of the Kadyrov Chechen State University
ORCID ID: 0000-0002-3679-520X
E-mail: shonoarsby@yahoo.com
Kudusov Kerim Musaevich,
Applicant, Department of Hospital Surgery, Kabardino-Balkarian State University named after Kh.M. Berbekov
ORCID ID: 0000-0001-6390-7361
E-mail: kerim-kudusov@mail.ru
Information about support in the form of grants, equipment, medications
The author did not receive financial support from manufacturers of medicines and medical equipment
Conflicts of interest: No conflict
Address for correspondence:
Vaganov Aleksey Gennadievich
Candidate of Medical Sciences, Associate Professor of the Department of Hos- pital Surgery, Kabardino-Balkarian State University named after Kh.M. Berbek- ov; Associate Professor of the Department of International Medical Education, Kadyrov Chechen State University
360004, Russian Federation, Nalchik, Chernyshevsky str., 173
Tel.: +7 (916) 2371477
E-mail: aleksejvaganov4@gmail.com
This work is licensed under a Creative Commons Attribution 4.0 International License.
Materials on the topic:
- CLINICAL AND IMMUNOLOGICAL PARALLELS IN LONG-TERM NON-HEALING WOUNDS OF PATIENTS WITH DIABETES MELLITUS
- OPTIMIZED PERIOPERATIVE MANAGEMENT (FAST-TRACK, ERAS) TO ENHANCE POSTOPERATIVE RECOVERY IN PANCREATICODUODENECTOMY
- ACUTE CALCULOUS CHOLECYSTITIS COMPLICATED BY NONSPECIFIC REACTIVE HEPATITIS AND JAUNDICE: CURRENT TRENDS IN DIAGNOSIS AND TREATMENT
- CONTEMPORARY DIAGNOSIS OF HEPATIC HYDATID ECHINOCOCCOSIS
- COMPLEX CLINICAL SCENARIOS IN ABDOMINAL SURGERY: A CASE REPORT
- ACUTE ADHESIVE SMALL BOWEL OBSTRUCTION: ROLE OF DOPPLER ULTRASONOGRAPHY IN PATIENT MANAGEMENT
- APPLICATION OF EXTRACORPOREAL DETOXIFICATION METHODS IN THE COMPLEX TREATMENT OF PATIENTS WITH INFECTED PANCREATIC NECROSIS
- RETROSPECTIVE ANALYSIS OF THE SURGICAL TREATMENT OUTCOMES FOR DIFFUSE PERITONITIS
- PREDICTION OF PERSISTENT PERITONITIS IN THE POSTOPERATIVE PERIOD
- REASONS FOR UNSATISFACTORY TREATMENT RESULTS OF ACUTE PURULENT DESTRUCTIVE LUNG DISEASES IN PATIENTS WITH SARS-COV-2 INFECTION