Obstetrics and Gynecology

doi: 10.25005/2074-0581-2021-23-1-12-17
Reserves for improving perinatal indicators by analyzing the outcomes of preterm labor

F.R. Ishan-Khodzhaeva, M.Ya. Kamilova

Tajik Scientific Research Institute of Obstetrics, Gynecology and Perinatology, Dushanbe, Republic of Tajikistan

Objective: Outline ways to improve perinatal outcomes as a result of analysis of the structure and methods of delivery in preterm labor (PL).

Methods: A retrospective analysis of the birth histories of women with PL and their newborns who were admitted to the clinic of the Research Institute in 2019, as well as an analysis of the indicators of annual reports for 2016-2019. The obtained data were processed by the methods of variation statistics.

Results: The absence of a decrease in the frequency of PL in the dynamics of the studied years was shown. It was found that in the 3rd level hospital, PL due to the need for early delivery prevails over spontaneous PL. Late PLs are recorded in every 2nd woman, PL – in every 3rd woman, early PL – in 14- 16%, and very early PL – in 10% of cases. Perinatal outcomes improve with increasing gestational age and fetal weight. Respiratory distress syndrome, asphyxia and cerebral hemorrhage were the leading causes of early neonatal mortality.

Conclusion: To further improve the perinatal outcomes of PL, actions are required to optimize the management of women with PR, providing for the possibility of delaying, preventing respiratory distress syndrome, improving blood flow in the mother-placenta-fetus system, taking into account individual approaches, as well as delivery techniques.

Keywords: Premature birth, spontaneous premature birth, the need for early delivery, early neonatal mortality, birth weight, gestational age.

Download file:


References
  1. Radzinskiy VE. Akusherskaya agressiya [Obstetric aggression]. Moscow, RF: Status Praesens; 2017. 872 p.
  2. Radzinskiy VE, Kostin IN, Olenev AS, Gagaev ChG, Parygina AN, Gavrilova AA, i dr. Prezhdevremennye rody – nereshyonnaya mirovaya problema [Premature birth is an unresolved global problem]. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie. 2018;6(S3):55-64. Available from: https://doi. org/10.24411/2303-9698-2018-13909
  3. Chawanpaiboon S, Vogel JP, Moller A-B, Lumbiganon P, Petzold M, Hogan D, et al. Global, regional, and national estimates of levels of preterm birth in 2014: A systematic review and modelling analysis. Lancet Global Health. 2019;7:37-46.
  4. Radzinskiy VE, Orazmuradov AA, Savenkova IV, Damirova KF, Haddad H. Prezhdevremennye rody – nereshyonnaya problema XXI veka [Premature birth is an unresolved problem in 21st century]. Kubanskiy nauchnyy meditsinskiy vestnik. 2020;27(4):27-37. Available from: https://doi.org/10.25207/1608- 6228-2020-27-4-27-37
  5. Duby J, Sharma R, Bhutta ZA. Opportunities and challenges in global perinatal research. Neonatology. 2018;114(2):93-102.
  6. Gavrilova AA, Parygina AN. Sverkhrannie i rannie prezhdevremennye rody: spornye voprosy [Early and early preterm labor: controversial issues]. Health and Education Millennium. 2018;20(1):24-8. Available from: https://doi. org/10.26787/nydha-2226-7425-2018-20-1
  7. Dudina AYu, Tskhay VB, Svirskaya SV, Konovalov VN. Analiz pokazatelya ranney neonatal’noy smertnosti v regional’nom uchrezhdenii rodovspomozheniya tret’ey gruppy [Analysis of the rate of early neonatal mortality in a regional obstetric facility of the third group]. Mat’ i ditya v Kuzbasse. 2018;4:63-9.
  8. Kosyakova OV, Bespalova ON. Profilaktika i terapiya ugrozhayushchikh prezhdevremennykh rodov pri mnogoplodii [Prevention and therapy of threatening premature birth in multiple pregnancies]. Zhurnal akusherstva i zhenskikh bolezney. 2019;68(4):55-70. Available from: https://doi.org/10.17816/ JOWD68455-70
  9. Leow SM, Di Quinzio MKW, Ng ZL, Brennecke SP, Arbel N, Georgiou HM. Preterm birth prediction in asymptomatic women at mid-gestation using a panel of novel protein biomarkers: The Prediction of PreTerm Labor (PPeTaL) study. Am J Obstet Gynecol MFM. 2020;2(2):100084. Available from: https:// doi.org/10.1016/j.ajogmf.2019.100084
  10. Oh KJ, Kim SM, Hong JS, Maymon E, Erez O, Panaitescu B, et al. Twenty-four percent of patients with clinical chorioamnionitis in preterm gestations have no evidence of either culture-proven intraamniotic infection or intraamniotic inflammation. Am J Obstet Gynecol. 2017;216(6):604-11. Available from: https://doi.org/10.1016/j.ajog.2017.02.035
  11. Gorina KA, Khodzhaeva ZS, Belousov DM, Baranov II, Gokhberg YaA, Pashchenko AA. Prezhdevremennye rody: proshlye ogranicheniya i novye vozmozhnosti [Premature birth: past limitations and new opportunities]. Akusherstvo i ginekologiya. 2020;1:12-9.
  12. Robson M, Murphy M, Byrne F Quality assurance: The 10-Group Classification System (Robson classification), induction of labor, and cesarean delivery. Int J Gynaecol Obstet. 2015;131(Suppl 1):S23-7. Available from: https://doi. org/10.1016/j.ijgo.2015.04.026
  13. Kuzibaeva RK. Dlina sheyki matki, kak prediktor prezhdevremennykh rodov [The length of the cervix as a predictor of premature birth]. Zdravookhranenie Tadzhikistana. 2015;2:55-62.
  14. Saidzhjalilova DD, Ermatova KhAK. Nekotorye aspekty razvitiya prezhdevremennyh rodov [Some aspects of development the premature labours]. Biologiya i integrativnaya meditsina. 2016;5:69-73.
  15. Kayumova DT, Rakhmatova NS. Perinatal’nye iskhody pri prezhdevremennykh rodakh [Perinatal outcomes in preterm labor]. Biologiya i integrativnaya meditsina. 2017;2:90-6.
  16. Kayumova DT, Rakhmatova NS. Perinatal’nye iskhody pri prezhdevremennykh rodakh [Perinatal outcomes in preterm labor]. Biologiya i integrativnaya meditsina. 2017;2:90-6.
  17. Usynina AA, Postoev VA, Odland IO, Menshikova LI, Pylaeva ZhA, Pastbina IM, i dr. Vliyanie mediko-sotsial’nykh kharakteristik i stilya zhizni materey na risk prezhdevremennykh rodov v arkticheskom regione Rossiyskoy Federatsii [The effect of medical social characteristics and style of life of mothers on premature delivery risks in the arctic region of the Russian Federation]. Problemy sotsial’noy gigieny, zdravookhraneniya i istorii meditsiny. 2018;26(5):302-6. Available from: https://doi.org/10.32687/0869- 866X-2018-26-5-302-306

Author information:


Ishan-Khodzhaeva Farangis Rustamovna
Candidate of Medical Sciences, Researcher, Obstetric Department, Tajik Scientific-Research Institute of Obstetrics, Gynecology and Perinatology
ORCID ID: 0000-0002-9211-1124
E-mail: kachyona@mail.ru

Kamilova Markhabo Yadgarovna
Doctor of Medical Sciences, Associate Professor, Head of Obstetric Department, Tajik Scientific-Research Institute of Obstetrics, Gynecology and Perinatology
Scopus ID: 6507463534
ORCID ID: 0000-0002-2525-8273
Author ID: 867673
SPIN-код: 2527-2877
E-mail: marhabo1958@mail.ru

Information about support in the form of grants, equipment, medications

The work was carried our according to the plan of scientific research works of Tajik Scientific-Research Institute of Obstetrics, Gynecology and Perinatology (registration number – 0119TJ00997). The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:


Kamilova Markhabo Yadgarovna
Doctor of Medical Sciences, Associate Professor, Head of Obstetric Department, Tajik Scientific-Research Institute of Obstetrics, Gynecology and Perinatology

734002, Republic of Tajikistan, Dushanbe, Tursunzade Str., 31

Tel.: +992 (935) 009425

E-mail: marhabo1958@mail.ru

Materials on the topic: