Cardiovascular Surgery
doi: 10.25005/2074-0581-2026-28-1-238-251
SURGICAL TREATMENT OF THORACIC OUTLET SYNDROME
1Republican Scientific Center for Cardiovascular Surgery, Dushanbe, Republic of Tajikistan
2Department of Surgical Diseases No. 2 named after Academician N.U. Usmanov, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Objective: The study aimed to optimize management tactics and the choice of surgical interventions to improve treatment outcomes for patients with extravascular compression of the neurovascular bundle (NVB) in thoracic outlet syndrome (TOS).
Methods: The results of complex diagnostics and treatment were studied in 521 patients (mean age 31.2±2.6 years; 27.1% (n=131) men and 74.9% (n=390) women) with various forms of TOS. Costoclavicular syndrome (CCS) was present in 51.8% (n=270) patients, complete accessory cervical rib (ACR) in 26.9% (n=140), rudimentary cervical rib (RCR) in 12.8% (n=67), scalene syndrome (SS) in 5.0% (n=26), and pectoralis minor syndrome (PMS) in 3.5% (n=18). Raynaud's phenomenon (RP) was also observed in 63.0% (n=328) patients. To diagnose TOS and the severity of NVB compression, functional tests, nitroglycerin and cold tests, and imaging methods – radiography, CT, duplex scanning with Doppler blood flow mapping, and electroneuromyography (ENMG) – were used.
Results: Clinical manifestations of TOS depended on the compression component. The arterial form presented with positional ischemia of the arm and thromboembolism of the palmar arterial arch. Cases with predominant nerve compression presented with shoulder girdle pain, hand muscle atrophy, and rapid upper limb fatigue. The venous form was characterized by hypertension in the subcutaneous venous system, often with thrombotic occlusion of the axillary-subclavian segment. Decompression surgeries were performed for all forms of TOS; in 339 cases, these were supplemented by upper thoracic sympathectomy, and in 16 cases by arterial revascularization. There were no fatalities during the hospital period. Intraoperative complications occurred in 2.5% (n=13) of patients, and early postoperative complications occurred in 7.7% (n=40). Long-term positive results were recorded in 91.9% of patients with CCS, 90.7% with ACR, 83.6% with RCR, and 100.0% with SS and PMS.
Conclusion: Common features across all types of TOS included NVB compression with corresponding clinical manifestations, combined with alternating bouts of vasospasm (63.0%). Optimized management tactics and surgical methods for TOS have improved the quality of specialized care. The high rate of successful outcomes across all forms of TOS demonstrates the effectiveness of decompression surgery.
Keywords: Thoracic outlet syndrome, diagnosis, arterial complications, rib resection, decompression, cervicothoracic sympathectomy.
References
-
1. DiLosa KL, Humphries MD. Epidemiology of thoracic outlet syndrome. Semin Vasc Surg. 2021;34(1):65-70. https://doi.org/10.1053/j.semvascsurg.2021.02.008
2. Shalan A, El-Basty A, Al-Saadi N, Popplewell M, Wall M, Hobbs S, et al. Thoracic outlet syndrome, United Kingdom: A retrospective review of practice. Ann Vasc Surg. 2025;114:74-82. https://doi.org/10.1016/j.avsg.2025.01.031
3. Ziapour B, Ranjbar K, Tian T, Thompson RW, Salehi P. A systematic review and meta-analysis of surgical approaches for venous thoracic outlet syndrome. J Surg Res. 2025;306:306-16. https://doi.org/10.1016/j.jss.2024.12.027
4. Issa TZ, Lin JS, Herrera F, Mailey B. Trends in the surgical management of thoracic outlet syndrome. Hand (NY). 2024;19(3):367-73. https://doi.org/10.1177/15589447221141479
5. Altoijry A, AlGhofili H, Iqbal K, Altuwaijri TA, Alsheikh S, AlHamzah M, et al. Vascular thoracic outlet syndrome: Registry of 30-years of patient's outcomes at King Saud University Medical City, Riyadh, Saudi Arabia. Saudi Med J. 2022;43(7):743-50. https://doi.org/10.15537/smj.2022.43.7.20220336
6. Boglione M, Ortíz R, Teplisky D, Giuseppucci C, Korman L, Reusmann A, Barrenechea M. Surgical treatment of thoracic outlet syndrome in pediatrics. J Pediatr Surg. 2022;57(9):29-33. https://doi.org/10.1016/j.jpedsurg.2021.08.017
7. Sultanov DD, Tukhtaev FM, Kurbanov NR, Sadriev ON. Sindrom verkhney grudnoy apertury [Syndrome of upper thoracic aperture]. Vestnik Avitsenny [Avicenna Bulletin]. 2014;3:121-7.
8. Falkoner MA, Weddel G. Costoclavicular compression of the subclavian artery and vein. Lancet. 1943;2:539-43. https://doi.org/10.1016/S0140-6736(00)72668-7
9. Jones MR, Prabhakar A, Viswanath O, Urits I, Green JB, Kendrick JB, et al. Thoracic outlet syndrome: A comprehensive review of pathophysiology, diagnosis, and treatment. Pain Ther. 2019;8(1):5-18. https://doi.org/10.1007/s40122-019-0124-2
10. Savelyev VS, Zatevakhin II, Prokuboskiy VI. Sheynoe rebro kak prichina emboli arteriy verkhney konechnosti [Cervical rib as a cause of embolies of the upper extremity]. Khirurgiya. 1975;3:16-21.
11. Maqbool T, Novak CB, Jackson T, Baltzer HL. Thirty-day outcomes following surgical decompression of thoracic outlet syndrome. Hand (NY). 2019;14(1):107-13. https://doi.org/10.1177/1558944718798834
12. Ransom EF, Minton HL, Young BL, He JK, Ponce BA, McGwin G, et al. Intermediate and long-term outcomes following surgical decompression of neurogenic thoracic outlet syndrome in an adolescent patient population. Hand (NY). 2022;17(1):43-9. https://doi.org/10.1177/1558944719901319
13. Gaibov AD, Kakhorov AZ, Sadriev ON, Yunusov KhA. Khirurgicheskoe lechenie sindroma verkhney grudnoy aperturi [Surgical treatment of thoracic outlet syndrome]. Vestnik khirurgii im. I.I. Grekova. 2015;174(1):78-83.
14. Lee JT, Dua MM, Chandra V, Hernandez-Boussard TM, Illig KA. Surgery for thoracic outlet syndrome: a nationwide perspective. J Vasc Surg. 2011;53(6):100S-101S. https://doi.org/10.1016/j.jvs.2011.03.195
15. Ahmed AS, Lafosse T, Graf AR, Karzon AL, Gottschalk MB, Wagner ER. Modern treatment of neurogenic thoracic outlet syndrome: Pathoanatomy, diagnosis, and arthroscopic surgical technique. J Hand Surg Glob Online. 2023;5(4):561-76. https://doi.org/10.1016/j.jhsg.2022.07.004
Authors' information:
Sultanov Dzhavli Davronovich,
Doctor of Medical Sciences, Full Professor, Deputy Director for Science, Republican Scientific Center for Cardiovascular Surgery; Professor of the Department of Surgical Diseases No. 2 named after Academician N.U. Usmanov, Avicenna Tajik State Medical University
Researcher ID: AAC-7784-2019
Scopus ID: 36922139600
ORCID ID: 0000-0001-7935-7763
SPIN: 9762-8395
Author ID: 445360
E-mail: sultanov57@mail.ru
Gaibov Alidzhon Dzhuraevich,
Corresponding Member of National Academy of Sciences of Tajikistan, Doctor of Medical Sciences, Full Professor, Professor of the Department of Surgical Diseases No. 2 named after Academician N.U. Usmanov, Avicenna Tajik State Medical University
Researcher ID: AAC-9879-2020
Scopus ID: 6602514987
ORCID ID: 0000-0002-3889-368X
SPIN: 5152-0785
Author ID: 293421
E-mail: gaibov_a.d@mail.ru
Rakhmonov Dzhamakhon Akhmadovich,
Candidate of Medical Sciences, Director, Republican Scientific Center for Cardiovascular Surgery
Researcher ID: AAT-2441-2020
ORCID ID: 0000-0002-4427-0155
SPIN: 4201-0747
Author ID: 1077348
E-mail: jama-7878@mail.ru
Nematzoda Okildzhon,
Candidate of Medical Sciences, Associate Professor of the Department of Surgical Diseases No. 2 named after Academician N.U. Usmanov, Avicenna Tajik State Medical University; Leading Researcher, Republican Scientific Center for Cardiovascular Surgery
Researcher ID: F-8729-2018
Scopus ID: 56469644700
ORCID ID: 0000-0001-7602-7611
SPIN: 2408-9107
Author ID: 929575
E-mail: sadriev_o_n@mail.ru
Makhmadalizoda Fayziddin
Makhmadali, Candidate of Medical Sciences, Applicant, Republican Scientific Center for Cardiovascular Surgery
ORCID ID: 0000-0001-5954-9522
SPIN: 7517-0607
Author ID: 916-624
E-mail: dr.Fayzidin@mail.ru
Information about support in the form of grants, equipment, medications
The authors did not receive financial support from manufacturers of medicines and medical equipment
Conflicts of interest: No conflict
Address for correspondence:
Sultanov Dzhavli Davronovich
Doctor of Medical Sciences, Full Professor, Deputy Director for Science, Repub- lican Scientific Center for Cardiovascular Surgery; Professor of the Department of Surgical Diseases No. 2 named after Academician N.U. Usmanov, Avicenna Tajik State Medical University
734003, Republic of Tajikistan, Dushanbe, Sanoi str., 33
Tel.: +992 (918) 334115
E-mail: sultanov57@mail.ru
This work is licensed under a Creative Commons Attribution 4.0 International License.
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