Surgery

doi: 10.25005/2074-0581-2018-20-1-90-96
POSTOPERATIVE PNEUMONIA: PREVENTION AND TREATMENT IN URGENT ABDOMINAL SURGERY

D.A. Abdulloev, D.E. Madzhidov, M.Kh. Nabiev, Kh.Sh. Shaymardanov

Department of General Surgery № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan

Objective: Preventive maintenance and treatment of postoperative pneumonia in patients with urgent abdominal pathology.

Methods: The results of examination and treatment of 86 patients with postoperative pneumonia (PP) for the period from 2005 to 2017 analyzed. There were 51 men (59.3%), women – 35 (40.7%). All patients were operated for the diffuse peritonitis caused by acute destructive appendicitis (n=21), perforated gastroduodenal ulcer (n=10), strangulated ventral hernia (n=4), acute intestinal obstruction (n=19), destructive forms of acute calculous cholecystitis (n=18) and acute destructive pancreatitis (n=14). In addition, the work presents the results of the application of the preventive measures developed by authors in 70 patients with urgent diseases of the abdominal cavity without PP.

Results: To reduce the frequency of PP in patients with urgent surgical diseases of the abdominal cavity, complicated by intraperitoneal hypertension syndrome and enteral insufficiency, a method of antegrade intubation of the small intestine has been developed. In cases when after approaching of the edges of laparotomic wounds, the intra-abdominal pressure was above 15 mm Hg, the operation completed by hemming to the edges of the aponeurosis using a polypropylene mesh. The use of preventive endoprosthetics allowed to increase the volume of the abdominal cavity and, thereby, to level out the high standing of the diaphragm and the lung compressions, which was a surgical preventive maintenance of PP. After completion of the operation, in 22 cases, a catheterization of the small intestine mesentery was performed with subsequent introduction of 10 mg of serotonin adipate twice daily with a microdose jet pump SN-50. The patients observed the resolution of paresis on the second day after the surgery.

Conclusion: Proposed measures for the prevention of PP allow to significantly improve the immediate results of surgical treatment of urgent diseases of the abdominal cavity by reducing the incidence of nonspecific complications. The use of serotonin adipate promotes the normalization of automatism and contractile activity of the smooth muscles of the intestine and allows reducing the frequency of complications and lethality among this complex category of patients.

Keywords: Postoperative pneumonia, abdominal cavity, serotonin adipate.

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References
  1. Bogomolova NS, Kuznetsova SM, Bolshakov LV. Rol' mikrobiologicheskogo monitoringa i lekarstvennogo anamneza v effektivnosti antibiotikoprofilaktiki i antibiotikoterapii infektsionnykh oslozhneniy posle rekonstruktivnykh operativnykh vmeshatel'stv [Role of microbiological monitoring and drug history in the effectiveness of antibiotic prophylaxis and antibiotic therapy of infectious complications after reconstructive surgical interventions]. Anesteziologiya i reanimatologiya. 2015;2:20-6.
  2. Volkov VE, Volkov SV, Zhamkov GV, Zhamkov DG, Yakovleva AV. Plevrolyogochnye oslozhneniya u bol'nykh ostrym nekroticheskim pankreatitom [Pleuropulmonary complications in patients with acute necrotic pancreatitis]. Zdravookhranenie Chuvashii. 2017;3:61-3.
  3. Egorova VN, Trofimov VI. Rekombinantnyy interleykin-2 (ronkoleykin®) v lechenii tyazhyoloy pnevmonii [Recombinant inter-leukin-2 (Roncoleukin®) in the treatment of severe pneumonia]. Retsept. 2012;2:90-103.
  4. Leushin KYu, Bagishev RA. Profilaktika ventilyator–assotsiirovannoy pnevmonii u patsientov, nakhodyashchikhsya na dlitel'noy IVL [Pre-vention of ventilator-associated pneumonia in patients on long-term mechanical ventilation]. Vestnik intensivnoy terapii. 2011;3.55-8.
  5. Dibirov MD, Rodionov IE, Kakubava MR. Korrektsiya vnutribryushnoy gipertenzii i mikrotsirkulyatsii u bol'nykh ostroy kishechnoy neprokhodimost'yu starcheskogo vozrasta [Correction of intra-abdominal hypertension and microcirculation in patients with acute intestinal obstruction of senile age]. Moskovskiy khirurgicheskiy zhurnal. 2012;3:9-14.
  6. Ignatyev VA, Kiselyova EA, Zarembo IA, Tsvetkova LN, Kochergina TA, Konev VG, i dr. Pnevmoniya u patsientov pozhilogo i starcheskogo vozrasta [Pneumonia in elderly and senile patients]. Klinicheskaya gerontologiya. 2008;6:27-9.
  7. Chuchalin AG. Pnevmoniya: aktual'naya problema meditsiny XXI veka [Pneumonia: an urgent problem of medicine of the XXI century]. Pul'monologiya. 2015;2:133-42.
  8. Shano VP, Gladkaya SV, Gumenyuk IV. Profilaktika abdominal'nogo kompartment-sindroma v sosudistoy khirurgii [Prevention of abdominal compartment syndrome in vascular surgery]. Vestnik neotlozhnoy i vosstanovitel'noy meditsiny. 2010;3:336-8.
  9. Gelfand BR, Protsenko DN, Ignatenko OV. Sindrom intraabdominal'noy gipertenzii [Syndrome of intra-abdominal hypertension]. Meditsina neotlozhnykh sostoyaniy. 2008;5:94-9.
  10. Belokonev VI, Ginzburg LB, Katkov SA. Sposoby profilaktiki abdominal'nogo kompartment-sindroma u bol'nykh s ostroy kishechnoy neprokhodimost'yu i peritonitom [Methods of preventing abdominal compartment syndrome in patients with acute intestinal obstruction and peritonitis]. Vestnik Sankt-Peterburgskogo universiteta. 2008;2:128-34.
  11. Malyuga VYu, Klimov AE, Fyodorov AG, Gaboyan AS, Davydova SV, Barkhudarov AA, i dr. Neposredstvennye i otdalyonnye rezul'taty khirurgicheskogo i endoskopicheskogo lecheniya bol'nykh khronicheskim kal'kulyoznym pankreatitom [Immediate and remote results of surgical and endoscopic treatment of patients with chronic calculous pancreatitis]. Vestnik Avitsenny [Avicenna Bulletin]. 2010;4:106-10.
  12. Kurbonov KM, Nazirboev KR, Polvonov ShB, Yorov SK. Radikal'noe udalenie istochnika rasprostranyonnogo peritonita u bol'nykh s zabolevaniyami polykh organov [Radical removal of a source of wide-spread peritonitis in patients with diseases of hollow organs]. Vestnik Avitsenny [Avicenna Bulletin]. 2016;4:65-70.
  13. Brazhnikova EV. Organizatsiya meropriyatiy po profilaktike infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi, v khirurgicheskikh i reanimatsionnykh otdeleniyakh mnogoprofil'nogo statsionara [Organization of measures for the prevention of infections associated with the provision of medical care in the surgical and resuscitation departments of the multiprofile hospital]. Zamestitel' glavnogo vracha. 2014;6:80-9.
  14. Syomina NA, Kovalyova EP, Frolova NV, Korshunova GS, Akimkin VG. Profilaktika vnutribol'nichnykh infektsiy v statsionarakh khirurgicheskogo profilya (proekt novykh sanitarno-epidemiologicheskikh pravil) [Prevention of nosocomial infections in hospitals of the surgical profile (draft of new sanitary and epidemiological rules)]. Epidemiologiya i vaktsinoprofilaktika. 2008;4:23-7.
  15. Tipisev DA, Gorobets ES, Gruzdev VE, Anisimov MA, Borovkova NB, Kochkovaya EO. Vsegda li neobkhodimo prodlenie iskusstvennoy ventilyatsii lyogkikh posle perenesyonnoy massivnoy krovopoteri v planovoy khirurgii: argumenty i fakty nablyudeniy odnoy kliniki [Is it always necessary to prolong artificial ventilation after a massive loss of blood in the planned surgery: the arguments and facts of observations of one clinic]. Vestnik intensivnoy terapii. 2016;4:52-8.
  16. Bhama AR, Batool F, Ferraro J, Cleary RK, Collins SD. Risk factors for postoperative complications following diverting loop ileostomy takedown. Journal of Gastrointestinal Surgery. 2017;12:2048-55.
  17. Berezhnova TA. Zabolevaemost' vnutribol'nichnymi infektsiyami v lechebno-profilakticheskikh uchrezhdeniyakh i faktory riska .[The incidence of nosocomial infections in medical and preventive institutions and risk factors]. Vestnik eksperimental'noy i klinicheskoy khirurgii. 2010;4:440-1.
  18. Demeshchenko BA, Rudnov VA, Bagin VA, Rozanova SM, Frolova ZA. Ventilyator-assotsiirovannaya pnevmoniya u patsientov s abdominal'nym sepsisom: faktory riska, osobennosti etiologii i prognoz [Ventilator-associated pneumonia in patients with abdominal sepsis: risk factors, features of etiology and prognosis]. Ural'skiy meditsinskiy zhurnal. 2008;7:4-11.
  19. Miller SV, Vinnik YuS, Beletskiy II, Markelova NM. Klinicheskie rezu-l'taty lecheniya ostrogo kholetsistita, oslozhnyonnogo kholedokho-litiazom, u patsientov s vysokim operatsionnym riskom [Clinical results of treatment of acute cholecystitis complicated by choledocholithiasis in patients with high operational risk]. Sibirskoe meditsinskoe obozrenie. 2009;4:41-5.
  20. Bayalieva AZh, Pasheev AV, Shpaner RYa, Akhmadeev RR. Neinvazivnaya ventilyatsiya lyogkikh v profilaktike i lechenii posleoperatsionnykh respiratornykh narusheniy [Noninvasive ventilation of the lungs in the prevention and treatment of postoperative respiratory disorders]. Obshchaya reanimatologiya. 2010;2:75-80.
  21. Miziev IA, Zekoreeva LN. Nozokomial'naya pnevmoniya u khirurgicheskikh bol'nykh [Nosocomial pneumonia in surgical patients]. Annaly khirurgii. 2008;5:42-6.
  22. Klester EB, Klester K, Babushkin IE. Healthcare-associated pneumonia: comparative characteristics with communityacquired pneumonia. European Respiratory Journal. 2015;59:2573.

Authors' information:


Abdulloev Dzhamoliddin Abdulloevich,
Doctor of Medical Sciences, Professor of the Department of General Surgery № 2, Avicenna TSMU

Madzhidov Dzhamshed Emomalievich,
Competitor of the Department of General Surgery № 2 Avicenna TSMU

Nabiev Muzaffar Kholnazarovich,
Candidate of Medical Sciences, Head of the Department of General Surgery № 2, Avicenna TSMU

Shaymardanov Khayyam Shukhratovich,
Assistant of the Department of General Surgery № 2, Avicenna TSMU

Conflicts of interest: No conflict

Address for correspondence:


Nabiev Muzaffar Kholnazarovich

Candidate of Medical Sciences, Head of the Department of General Surgery № 2, Avicenna TSMU

734003, Republic of Tajikistan, Dushanbe, Rudaki Ave., 139

Tel.: (+992) 987 256060

E-mail: myzaffar.nabiev.2017@mail.ru

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