Endocrinology

doi: 10.25005/2074-0581-2022-24-4-562-568
AUTOIMMUNE POLYGLANDULAR SYNDROME PREVALENCE IN TOLUCA, MEXICO

Concepción Carrillo LE1, Rodríguez Piña MD1, Pineda González MG1, García Ocampo F1, Mendieta Zerón H1,2

1Faculty of Medicine, Autonomous University of the State of Mexico, Toluca, Mexico
2Maternal-Perinatal Hospital «Mónica Pretelini Sáenz», Toluca, Mexico

Objective: Autoimmune polyglandular syndromes (APS) are endocrinopathies whose main characteristic is the loss of immune tolerance. The objective of this work was to report the APS prevalence in an Internal Medicine Service from Toluca, Mexico.

Methods: This was a descriptive and retrospective study. Medical files from the service of Internal Medicine at Ciprés Grupo Médico CGM SC (CGM), Toluca, Mexico, in a period of 11 years were analyzed. The prevalence of APS was obtained taking into account all the patients seen in the mentioned period and in particular considering only the following diseases: diabetes mellitus, thyroiditis and Addison's disease.

Results: From 2000 clinical files, five cases (0.25%) are presented according to the criteria and clinical manifestations. APS detection among patients who were treated for endocrine pathology (diabetes mellitus = 807, thyroiditis = 473, and hypocortisolism = 5) were 5 in 1285 (0.38%).

Conclusion: APS-2 is the most common type of APS in a common Internal Medicine service in Toluca, Mexico.

Keywords: Autoimmune polyglandular syndrome, hypothyroidism, type 1 diabetes mellitus.

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Author information:


Luis Edgar Concepción Carrillo
MD Faculty of Medicine, Autonomous University of the State of Mexico, Toluca, Mexico
ORCID ID: 0000-0002-2195-022X
E-mail: luisedgarcoca@gmail.com

Miriam Deyanira Rodríguez Piña
MD Faculty of Medicine, Autonomous University of the State of Mexico, Toluca, Mexico
ORCID ID: 0000-0003-1882-2814
E-mail: miriam_drp@hotmail.com

Mariana Guadalupe Pineda González
MD Faculty of Medicine, Autonomous University of the State of Mexico, Toluca, Mexico
ORCID ID: 0000-0003-1013-9500
E-mail: mariana.pineda2910@gmail.com

Fátima García Ocampo
MD Faculty of Medicine, Autonomous University of the State of Mexico, Toluca, Mexico
ORCID ID: 0000-0002-7034-8673
E-mail: faty.2000.14@gmail.com

Hugo Mendieta Zerón
PhD Faculty of Medicine, Autonomous University of the State of Mexico, Toluca, Mexico, and Maternal-Perinatal Hospital «Mónica Pretelini Sáenz»
ORCID ID: 0000-0003-3492-8950
E-mail: hmendietaz@gmail.com

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from companies manufacturing medications and medical equipment

Conflicts of interest: No conflict

Address for correspondence:


Hugo Mendieta Zerón
PhD Faculty of Medicine, Autonomous University of the State of Mexico, Toluca, Mexico, and Maternal-Perinatal Hospital «Mónica Pretelini Sáenz»

Paseo Tollocan Poniente 201, Universidad, 50010, Toluca, Mexico

E-mail: hmendietaz@gmail.com

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