Anesthesiology and Critical Care Medicine

doi: 10.25005/2074-0581-2022-24-3-298-305
THE IMPACT OF INTRAOPERATIVE NEUROPHYSIOLOGICAL MONITORING IN THYROID SURGERY ON THE CHOICE OF ANAESTHETIC AND RESUSCITATION OPTIONS

E.V. Volkov1,2, L. Kh. Batchaeva2, V.V. Fisher1,2, S.G. Chernyshyova3

1Department of Anesthesiology, Resuscitation and Emergency Medicine with a Course of Additional Postgraduate Education, Stavropol State Medical University, Stavropol, Russian Federation
2Stavropol Regional Clinical Hospital, Stavropol, Russian Federation
3Stavropol Emergency Hospital, Stavropol, Russian Federation

Objective: To assess the effect of intraoperative neurophysiological monitoring (IONM) on the incidence of life-threatening complications of the surgical treatment of thyroid diseases in the operating room and intensive care unit.

Methods: A retrospective analysis of the medical records of 212 patients aged 31 to 72 was carried out. Depending on the treatment modality, they were divided into two groups. In group I (study group, n=96), IONM was used during surgery, and in group II (control group, n=116) – the surgery was performed without IONM. The effectiveness of IONM was assessed based on the number of complications and tracheal reintubation in the postoperative period.

Results: IONM contributed to a statistically significant decrease in the number of postoperative complications. Thus, injury to the recurrent laryngeal nerve (RLN) was noted in 1 (1.0%) patient in the study group versus 17 (14.6%) in the control group (p<0.05); hoarseness was present in 3 (3.1%) and 35 (30.1%) cases in the study and control groups, respectively (p<0.05). In addition, although statistically insignificant, there was a reduced rate of tracheal reintubation: in two (2.1%) and (6.0%) patients in the study and the control groups, respectively (p>0.05). Of these, 5 (4.3%) patients needed surgeries due to bilateral injury to the RLN. The decrease in the incidence of complications, in turn, contributed to a reduction in both the average lengths of stays in the intensive care unit (6.2±0.5 days and 7.4±0.3 days in the study and the control groups, respectively, p>0.05) and the overall treatment time (59.1±1.7 and 121.3±4.8 patient days in the study and the control groups, respectively, p<0.05).

Conclusion: IONM in thyroid surgery can reduce the number of complications, such as damage to the recurrent laryngeal nerve, although it does not exclude them entirely. The data obtained allow us to recommend using IONM in everyday practice.

Keywords: Recurrent laryngeal nerve paralysis, the thyroid gland, neurophysiological monitoring, thyroidectomy, postoperative complications, tracheal reintubation.

Download file:


References
  1. Kurbonov S, Davlatov IA. Patomorfologicheskaya kharakteristika sosudistoy sistemy shchitovidnoy zhelezy pri diffuznom toksicheskom zobe [Pathomorphologic characteristics of thyroid gland vascular system at the diffuse toxic goiter]. Zdravookhranenie Tadzhikistana. 2018;2:29-33.
  2. Davlatov IA, Gulov MK, Kurbonov S. Morfometricheskaya kharakteristika parametrov komponentov shchitovidnoy zhelezy pri diffuznom toksicheskom zobe [Morphometric parameters characteristic of the components of the thyroid gland at diffuse toxic goiter]. Vestnik Akademii meditsinskikh nauk Tadzhikistana. 2019;9(1):12-7.
  3. Mirkhodzhaev IA, Komilov SO. Kachestvo zhizni bol'nykh, perenyosshchikh operatsiyu na shchitovidnoy zheleze [Quality of life of patients underwent thyroid surgery]. Biologiya i integrativnaya meditsina. 2021;5:22-33.
  4. Troshina EA, Platonova NM, Panfilova EA. Dinamika epidemio-logicheskikh pokazateley tireoidnoy patologii u naseleniya Rossiyskoy Federatsii: analiticheskiy otchyot za period 2009-2018 gg. [Dynamics of epidemiological indicators of thyroid pathology in the population of the Russian Federation: Analytical report for the period 2009-2018]. Problemy endokrinologii. 2021;67(2):10-9. Available from: https://doi.org/10.14341/probl12433
  5. Totoeva ZN. Analiz oslozhneniy posle razlichnykh operativnykh vmeshatel'stv na shchitovidnoy zheleze [Analysis of complications after various surgical interventions on the thyroid gland]. Endoskopicheskaya khirurgiya. 2014;20(6):33- 7.
  6. Dedov II, Melnichenko GA. Endokrinologiya: natsional'noe rukovodstvo. 2-e izd., pererab. i dop. [Endocrinology: National guidelines]. Moscow, RF: GEOTAR- Media; 2021. 1112 p.
  7. Puzin SN. Bolezni shchitovidnoy zhelezy kak prichina invalidnosti naseleniya [Diseases of the thyroid gland as a cause of disability in the population]. Vestnik Vserossiyskogo obshchestva spetsialistov po mediko-sotsial'noy ekspertize, reabilitatsii i reabilitatsionnoy ehkspertize. 2019;4:52-9.
  8. Uludag M, Aygun N, Kartal K, Citgez B, Besler E, Yetkin G, et al. Contribution of intraoperative neural monitoring to preservation of the external branch of the superior laryngeal nerve: A randomized prospective clinical trial. Langenbecks Arch Surg. 2017;402(6):965-76. Available from: https://doi.org/10.1007/ s00423-016-1544-7
  9. Vetshev PS, Yankin PL, Zhivotov VA, Poddubnyy EI, Prokhorov VD. Rezul'taty primeneniya intraoperatsionnogo neyromonitoringa vozvratnykh gortannykh nervov v khirurgii shchitovidnoy zhelezy [Results of intraoperative neuromonitoring of recurrent laryngeal nerves in thyroid surgery]. Vestnik Natsional'nogo mediko-khirurgicheskogo tsentra im. N.I. Pirogova. 2018;13(4):41-8. Available from: https://doi.org/10.25881/BPNMSC.2018.90.41.007
  10. Staubitz JI, Watzka F, Poplawski A, Riss P, Clerici T, Bergenfelz A, Musholt TJ, EUROCRINE® Council Effect of intraoperative nerve monitoring on postoperative vocal cord palsy rates after thyroidectomy: European multicentre registry-based study. BJS Open. 2020;4(5):821-9. Available from: https://doi. org/10.1002/bjs5.50310
  11. Zhu Y, Gao DS, Lin J, Wang Y, Yu L. Intraoperative neuromonitoring in thyroid and parathyroid surgery. J Laparoendosc Adv Surg Tech A. 2021;31(1):18-23. Available from: https://doi.org/10.1089/lap.2020.0293
  12. Makariin VA, Uspenskaya AA, Semyonov AA, Timofeeva NI, Chernikov RA, Sleptsov IV, i dr. Postoyannyy neyromonitoring gortannykh nervov pri operatsiyakh po povodu raka shchitovidnoy zhelezy [Permanent neuromonitoring of the laryngeal nerves during surgery for thyroid cancer]. Voprosy onkologii. 2019;65(3):342-8. Available from: https://doi.org/10.37469/0507-3758-2019- 65-3-342-348

Authors' information:


Volkov Evgeniy Vladimirovich
Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology, Resuscitation and Emergency Medicine with a Course of Additional Postgraduate Education, Stavropol State Medical University; Head of the Department of Anesthesiology and Intensive Care № 1, Stavropol Regional Clinical Hospital
ORCID ID: 0000-0002-9841-6930
SPIN: 2515-7594
Author ID: 909583
E-mail: volkov26@mail.ru

Batchaeva Laura Khalisovna
Anesthesiologist-Resuscitator, Stavropol Regional Clinical Hospital
ORCID ID: 0000-0002-4388-5430
E-mail: lbatchaeva312@gmail.com

Fisher Vasiliy Vladimirovich
Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology, Resuscitation and Emergency Medicine with a Course of Additional Postgraduate Education, Stavropol State Medical University; Deputy Chief Physician for Medical Work, Stavropol Regional Clinical Hospital
ORCID ID: 0000-0003-1494-1613
Author ID: 688363
E-mail: vvfisher26@gmail.com

Chernyshyova Svetlana Gennadievna
Anesthesiologist-Resuscitator, Stavropol Emergency Hospital
ORCID ID: 0000-0002-0463-2422
E-mail: cherns80@gmail.com

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:


Volkov Evgeniy Vladimirovich
Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology, Resuscitation and Emergency Medicine with a Course of Additional Postgraduate Education, Stavropol State Medical University; Head of the Department of Anesthesiology and Intensive Care № 1, Stavropol Regional Clinical Hospital

355029, Russian Federation, Stavropol, Semashko str., 1, building 1

Tel.: +7 (928) 0126095

E-mail: volkov26@mail.ru

Materials on the topic: