Literature Reviews
doi: 10.25005/2074-0581-2020-22-3-484-490
MYCOBACTERIOSIS: A REVIEW OF EVIDENCE-BASED CLINICAL MANIFESTATIONS AMONG HUMANS

F.S. Petrova1,2, I.V. Petrov1,3, T.Kh. Amirova1, L.V. Petrova1,4

1Department of Fundamental Medicine, Mari State University, Yoshkar-Ola, Russian Federation
2Regional Office of Rospotrebnadzor for the Republic of Tatarstan, Kazan, Russian Federation
3Department of Hygiene and Occupational Medicine, Kazan State Medical University, Kazan, Russian Federation
4Microbiological Laboratory, Republican TB Dispensary, Yoshkar-Ola, Russian Federation

The review presents data on proven clinical manifestations of the disease caused by non-tuberculosis mycobacteria. It was determined that pulmonary mycobacteriosis is one of the most common clinical forms of this mycobacterial infection, which is characterized by intoxication and respiratory syndromes. Dust in the air of the working area, as a professional factor, contributes to the emergence of pneumoconiosis and silicosis associated with mycobacteria. It is proved that M. avium has the ability to damage the intestinal mucosa, causing bacteremia and secondary damage to the bone marrow and spleen. The researchers point to the fact that non-tuberculosis mycobacteria can cause lymphadenopathy with lesions of the intraabdominal and cervical lymph nodes. Also, there is the possibility of mycobacteriosis of the skin. It is proved that mycobacterial infection contributes to the development of calcification of mitral, aortic valves and coronary arteries. It was determined that in the etiology of acute pancreatitis mycobacteriosis also plays definite role.

Keywords: Mycobacteriosis, non-tuberculosis mycobacteria, clinical presentations, epidemiology.

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Authors' information:

Petrova Firuza Salavatovna
Assistant of the Department of Fundamental Medicine, Mari State University; Expert Specialist, Regional Office of Rospotrebnadzor for the Republic of Tatarstan SPIN: 4662-2259 Author ID: 918963 Е-mail: lvps@bk.ru

Petrov Iliya Vladimirovich
Candidate of Medical Sciences, Associate Professor of the Department of Fundamental Medicine, Mari State University; Assistant of the Department of Hygiene and Occupational Medicine, Kazan State Medical University ORCID ID: 0000-0002-2097-5679 SPIN: 1405-9154 Author ID: 825031 Е-mail: ilia.v.petrov@mail.ru

Amirova Tanzilya Khafizovna
Candidate of Medical Sciences, Associate Professor of the Department of Fundamental Medicine, Mari State University Researcher ID: AAR-9860-2020 ORCID ID: 0000-0002-0666-7418 SPIN: 7099-5423 Author ID: 1057310 Е-mail: tanzilya.amirova.85@mail.ru

Petrova Lyudmila Vitalievna
Head of the Microbiological Laboratory, Republican TB Dispensary; Assistant of the Department of Biochemistry, Cell Biology and Microbiology, Mari State University SPIN: 4662-2259 Author ID: 918963 Е-mail: lvps@bk.ru

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Amirova Tanzilya Khafizovna
Candidate of Medical Sciences, Associate Professor of the Department of Fundamental Medicine, Mari State University

424000, Russian Federation, Republic of Mari El, Yoshkar-Ola, Pl. Lenin, 1

Tel.: +7 (902) 4337141

E-mail: tanzilya.amirova.85@mail.ru

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