Literature Reviews
doi: 10.25005/2074-0581-2020-22-3-491-497
APPLICATION OF PHOTODYNAMIC THERAPY IN TREATMENT OF MALIGNANT NEOPLASMS OF THE CENTRAL NERVOUS SYSTEM

A.A. Sufianov1,2, D.A. Murzaeva3, I.S. Shelyagin1,2, R.A. Sufianov1

1Department of Neurosurgery, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation
2Federal Center for Neurosurgery, Tyumen, Russian Federation
3Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russian Federation

World literature data dedicated to the problem of application of photodynamic therapy (PDT) in the neurooncology has been studied and analyzed, and also the prospects for development and improvement of surgical treatment for malignant neoplasms of CNS are covered. The following databases are used: PubMed, Web of Science, Scopus, MEDLINE, EMBASE, Biosis Citation Index, SciELO Citation Index, RSCI. Noted, that PDT treatment of tumors can be widely used in various areas of oncology demonstrating high efficiency and radical value. In particular, the method shows good treatment results for brain glioblastomas. At the same time, the use of modern photosensitizers and methods of delivering pharmaceutical drugs to affected cells in conjunction with the use of fiber optics makes it possible to minimize damage to surrounding tissues and possible neurological deficits.

Keywords: Photodynamic therapy, CNS tumors, minimally invasive interventions.

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Authors' information:

Sufianov Albert Akramovich
Doctor of Medical Sciences, Full Professor, Head of the Department of Neurosurgery, I.M. Sechenov First Moscow State Medical University; Chief Medical Officer, Federal Center for Neurosurgery
Scopus ID: 6603558501
ORCID ID: 0000-0001-7580-0385
SPIN: 1722-0448
Author ID: 446102
Е-mail: Sufianov@gmail.com

Murzaeva Dzhamilya Adilkhanovna
Resident, Pavlov First Saint Petersburg State Medical University
ORCID ID: 0000-0002-2801-4485
SPIN: 9618-6709
Author ID: 937283
Е-mail: dzhamilay22@mail.ru

Shelyagin Ivan Sergeevich
Resident, Department of Neurosurgery, I.M. Sechenov First Moscow State Medical University; Neurosurgeon, Federal Center for Neurosurgery
SPIN: 4188-2029
Author ID: 1043290
E-mail: sheliaginivan@outlook.com

Sufianov Rinat Albertovich
Assistant, Department of Neurosurgery, I.M. Sechenov First Moscow State Medical University
ORCID ID: 0000-0003-4031-0540
SPIN: 1204-2994
Author ID: 792245
Е-mail: Rinat.sufianov@gmail.com

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Murzaeva Dzhamilya Adilkhanovna
Resident, Pavlov First Saint Petersburg State Medical University

197022, Russian Federation, St. Petersburg, Lev Tolstoy str., 6-8

Tel.: +7 (929) 2623082

E-mail: dzhamilay22@mail.ru

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