Literature Reviews
doi: 10.25005/2074-0581-2019-21-3-480-488
MODERN ASPECTS OF DIAGNOSTICS AND SURGICAL TREATMENT OF HEPATIC ECHINOCOCCOSIS

Sh.Sh. Amonov1,2, D.A. Rakhmonov1,2, Z.Sh. Fayziev2, F.B. Bokiev2, F.A. Turakulov2, D.S. Sangov2

1Department of Surgical Diseases № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
2Department of Endoscopic Surgery, Republican Scientific Center for Cardiovascular Surgery, Dushanbe, Republic of Tajikistan

The review presents data on modern methods of diagnosis and surgical treatment of hepatic echinococcosis (HE). Focused attention, on such aspects of HE as frequency, structure, diagnostics, indications for the surgical treatment of hepatic cysts, ways of processing the residual cavity, intra-operative diagnosis of bile fistulas, use of special tools and prevention of recurrence of the disease. It should be noted that the frequency of postoperative complications and relapses of HE remains high. All methods of operations performed at HE have both advantages and disadvantages. So far, there are no proven advantages of access in literature for HE, depending on the specifics of the localization of the cyst. Besides, effective surgical treatment is hampered by a number of under-explored questions regarding the nature and scope of surgery, the way of processing cyst walls, the need for drainage or a method of eliminating the residual cavity, prevention, and treatment of internal bile fistulas.

Keywords: Hepatic echinococcosis, laparoscopy , mini-access, traditional access, surgical treatment.

Download file:

References
  1. Kolkin YaG. Modifitsirovannyy sposob likvidatsii ostatochnoy polosti posle operatsii na pecheni [Modified method for the elimination of the residual cavity after liver surgery]. Ukrainskiy zhurnal khiryrgii. 2010;2:257-9.
  2. Nishanov FN. Etiopatogeneticheskie aspekty retsidivnogo ekhinokokkoza pecheni i ego diagnostika [Etiopathogenetic aspects of recurrent liver echinococcosis and its diagnosis]. Vestnik khiryrgii im I.I. Grekova. 2011;2:91-4.
  3. Sangov DS, Nazarov FN, Gulmuradov TG. Videoendoskopicheskaya khirurgiya ekhinokokkoza pecheni [Video endoscopic surgery of liver echinococcosis]. Zdravookhranenie Tadzhikistana. 2013;3:53-7.
  4. Kholin AV, Amanbaeva GT, Kakishov YK. Diagnosticheskie vozmozhnosti KT i MRT v raspoznovanii al’veokokkoza i ekhinokokkoza pecheni [Diagnostic capabilities of CT and MRI in recognition of liver alveococcosis and echinococcosis]. Vestnik Kyrgyzsko-Rossiyskogo slavyanskogo universiteta. 2015;15(7):164-9.
  5. Salimov DS, Boymuradov OS, Karimov AM. Aktual’nye problemy diagnostiki doklinicheskikh form ekhinokokkovoy bolezni [Actual problems of diagnosis of preclinical forms of hydatid disease]. Izvestiya Akademii nauk Respubliki Tadzhikistan. Otdelenie biologicheskikh i meditsinskikh nauk. 2011;2:100-5.
  6. Gaibov AD, Kamolov AN, Mirzoev SA, Kalmykov EL, Aminov RS. Emboliya bifurkatsii aorty, vyzvannaya razorvavsheysya ekhinokokkovoy kistoy serdtsa [Bifurcation aortic embolism caused by a ruptured echinococcal heart cyst]. Kardiologiya i serdechno-sosudistaya khirurgiya. 2009;5:89-92.
  7. Gulmuradov TG, Sadriev ON, Abdurakhimov ZZ, Aminov RS. Uspeshnoe khirurgicheskoe lechenie patsientki s ekhinokokkozom levogo zhelydochka i pecheni [Successful surgical treatment of patients with echinococcosis of the left ventricle and liver]. Novosti khirurgii. 2016;24(3):298-302.
  8. Kalmykov EL, Gaibov AD, Sadriev ON, Safarova AN. Pervichnaya ekhinokokovaya kista myshts poyasnichnoy oblasti [Primary muscle hydatidosis of the lumbar region]. Novosti khiryrgii. 2016;24(6):610-6.
  9. Usmanov NU, Shamsiev NSh, Baratov AK. Mnozhestvennyy oslozhnyonnyy ekhinokokkoz perikarda [Multiple complicated echinococcosis of pericardium]. Grudnaya i serdechno-sosudistaya khirurgiya. 2000;1:69.
  10. Lloyd JB. Hepatic cystic echinococcosis. The Journal of the American Osteopathic Association. 2014;114(6):505.
  11. Aytanazarov MS. Diagnostika i lechenie oslozhnyonnogo ekhinokokkoza pecheni diafragmal’noy lokalizatsii [Diagnosis and treatment of complicated liver echinococcosis of diaphragmatic localization]. Vestnik Kyrgyzsko-Rossiyskogo slavyanskogo universiteta. 2014;14(10):70-2.
  12. Nazarov ShK, Rizoev VS. Videolaparoskopicheskaya tekhnologiya v lechenii ekhinokokkoza pecheni [Video laparoscopic technology in the treatment of liver echinococcosis]. Vestnik Akademii nauk Respubliki Tadjikistan. 2016;4:138-44.
  13. Kuchin YV. Gidativniy ekhinokokkoz pecheni. Puti uluchsheniya rezul’tatov khirurgicheskogo lecheniya [Hydraulic echinococcosis of the liver. Ways to improve the results of surgical treatment]. Trudy Astrakhanskoy meditsinskoy akademii. 2014;40:103-5.
  14. Chernikova EA, Ermakova LA, Kozlov SS, Ekhinokokkozy: podkhody k lecheniyu [Echinococcosis: treatment approaches]. Infektsionnye bolezni: novosti, mneniya, obuchenie. 2014;1:52-6.
  15. Rashidov FSh, Sangov DS, Amonov ShN. Videolaparoskopicheskaya ekhinokokkektomiya pecheni – pervye shagi [Video laparoscopic liver echinococcectomy – the first steps]. Vestnik Avitsenny [Avicenna Bulletin]. 2009;2:19-23.
  16. Farrokh D. Hepatic alveolar echinococcosis. Archives of Iranian Medicine. 2015;18(3):199-202.
  17. Gulov MK, Kalmykov EL, Zardakov SM, Mukhabbatov DK, Sadriev ON. Ekhinokokkoz pecheni: rol’ komp’yuternoy tomografii i morfologicheskoy diagnostiki sostoyaniya tkani pecheni [Liver hydatid disease: role of computer tomography and morphological changes of liver]. Rossiyskiy mediko-biologicheskiy vestnik imeni akademika I.P. Pavlova. 2016;24(4):104-11.
  18. Gulmuradov TG, Amonov ShSh, Prudkov MI, Sangov DS. Minimal’no-invazivnaya khirurgiya ekhinokokkoza pecheni [Minimally invasive surgery of liver echinococcosis]. Vestnik poslediplomnogo obrazovaniya v sfere zdravookhraneniya. 2015;2:29-3.
  19. Vafin AZ, Aydemirov AN. Osobennosti povtornykh operatsiy na pecheni pri retsidivakh ekhinokokkoza [Features of repeated operations on the liver with relapses of echinococcosis]. Al’manakh Instituta khirurgii im. A.V. Vishnevskogo. 2011;6(2):94-5.
  20. Bauomi IR. Evaluation of purified 27.5 kDa protoscolex antigen-based ELISA for the detection of circulating antigens and antibodies in sheep and human hydatidosis. Journal of Helminthology. 2015;89(5):577-83.
  21. Nishanov FN, Botirov FN, Otakuziev AK, Nishanov AZ. Etiopatogeneticheskie aspekty retsidivnogo ekhinokokkoza pecheni i ego diagnostika [Etiopathogenetic aspects of recurrent liver echinococcosis and its diagnosis]. Vestnik khirurgii im I.I. Grekova. 2011;2:91-4.
  22. Tamer GS, Dundar D, Uzuner H, Baydemir C. Evaluation of immunochromatographic test for the detection of antibodies against Echinococcosis granulosus. Medical Science Monitor. 2015;21(1):1219-22.
  23. Troyan VN, Tikhonov EV, Kovtun EA. Komp’yuternaya tomografiya v differentsial’noy luchevoy diagnostike ekhinokokkoza razlichnoy lokalizatsii [Computed tomography in the differential radiological diagnosis of echinococcosis of various localization]. Voenno-meditsinskiy zhurnal. 2010;6:44-5.
  24. Minosyan BA, Ivashev MN, Sergienko AV. Farmokodinamika al’bendazola [Pharmacodynamics of albendazole]. Sovremennye naykoyomkie tekhnologii. 2014;10:77-8.
  25. Ivanov SA, Korimasov EA, Meshkov SV. Varianty khirurgicheskoy taktiki pri lechenii sochetannogo ekhinokokkoza lyogkikh i pecheni [Variants of surgical tactics in the treatment of combined echinococcosis of the lungs and liver]. Izvestiya Samarskogo nauchnogo tsentra Rossiyskoy akademii nauk. 2015;17(1):517-20.
  26. Nazyrov FG, Devyatov AV, Akbarov MM, Makhmudov UM, Babadzhanov AKh. Khimioterapiya i problemy retsidivnogo ekhinokokkoza pecheni [Chemotherapy and problems of recurrent liver echinococcosis]. Annaly khirurgicheskoy gepatologii. 2011;16(4):19-24.
  27. Baraket O. Predictive factors of morbidity after surgical treatment of hydatid cyst of the liver. Arab Journal of Gastroenterology. 2014;15(3):119-22.
  28. Güreser AS. Evaluation of the radiological, biochemical and serological parameters of patients prediagnosed as cystic echinococcosis in Çorum, Turkey. Mikrobiyoloji Bülteni. 2015;49(2):231-9.
  29. Zogot SR, Akberov RF, Kim AB. Kompleksnaya luchevaya diagnostika ekhinokokkoza pecheni [Comprehensive radiation diagnosis of liver echinococcosis]. Prakticheskaya meditsina. 2012;58(3):75-7.
  30. Akhmedov SM, Ibrokhimov NK, Safarov BD, Rasulov NA. Rezektsiya pecheni pri ekhinokokkoze [Liver resection for echinococcosis]. Annaly khirurgicheskoy gepatologii. 2014;19(2):49-55.
  31. Skipenko OG, Polishchuk LO, Chekunov DA, Kim SYu. Proryv ekhinokokkovoy kisty v zhelchnye protoki, oslozhnyonnyy kholedokhoduodenal’nym svishchom [Breakthrough of an echinococcal cyst in the bile ducts, complicated by choledochoduodenal fistula]. Khirurgiya. 2012;7:80-2.
  32. Mukanteev TE. Laparoskopicheskaya ekhinokokkektomiya u patsientov s ekhinokokkozom pecheni [Laparoscopic echinococcectomy in patients with liver echinococcosis]. Kazanskiy meditsinskiy zhurnal. 2015;96(2):138-43.
  33. Kurbanov KM, Davlatov DE, Makhmadov FI, Azizov ZA. Diagnostika i taktika khirurgicheskogo lecheniya retsidivnogo ekhinokokkoza pecheni [Diagnosis and tactics of surgical treatment of recurrent liver echinococcosis]. Zdravookhranenie Tadzhikistana. 2014;2:36-43.
  34. Lashkarizadeh MR. Comparison of scolicidal effects of amphotericin B, silver nanoparticles, and foeniculum vulgare mill on hydatid cysts protoscoleces. Iranian Journal of Parasitology. 2015;2(10):206-12.
  35. Makhmadov FI. Maloinvazivnye vmeshatel’stva pri ekhinokokkoze pecheni [Minimally invasive interventions for liver echinococcosis]. Vestnik pedagogicheskogo universiteta. 2013;3:154-7.
  36. Karabulut K. Long term outcomes of intraoperative and perioperative albendazole treatment in hepatic hydatidosis: single center experience. Annals of Surgical Treatment and Research. 2014;2(87):61-5.
  37. Gulmuradov TG, Sangov DS, Nazarov FN. Endovideokhirurgicheskoe lechenie ekhinokokkoza pecheni [Endovideosurgical treatment of liver echinococcosis]. Nauchno-prakticheskiy zhurnal TIPPMK. 2013;3:18-22.
  38. Bodnya EI, Velieva TA. Instrumental’naya diagnostika ekhinokokkoza pecheni [Instrumental diagnosis of liver echinococcosis]. Klinicheskaya infektologiya i parazitologiya. 2014;2(9):124-32.
  39. Orlov OG, Prudkov MI, Krokhina NB. Khirurgicheskoe lechenie prostykh kist pecheni [Surgical treatment of simple liver cysts]. Vestnik Ural’skoy meditsinskoy akademii. 2009;3:112-6.
  40. Khadzhibaev AM, Anvarov KhE, Khashimov MA. Diagnostika i lechenie ekhinokokkoza pecheni, oslozhnyonnogo proryvom v zhelchnye puti [Diagnosis and treatment of liver echinococcosis, complicated by a breakthrough in the biliary tract]. Vestnik ekstrennoy meditsiny. 2010;4:15-8.
  41. Tappeh KH. Effect of different concentrations of hypertonic saline at different times on protoscoleces of hydatid cyst isolated from liver and lung. Turkish Society for Parasitology. 2011;3:148-50.
  42. Liu C. In vivo and in vitro efficacies of mebendazole, mefloquine and nitazoxanide against cyst echinococcosis. Parasitology Research. 2015;6:2213-22.
  43. Gulov MK. Klassifikatsiya oslozhnyonnogo ekhinokokkoza pecheni [Classification of complications of liver echinococcosis]. Vestnik Avitsenny [Avicenna Bulletin]. 2010;3:18-24.
  44. Babakulov KK, Aliev MZh, Kanietov AK. Khimioprofilaktika retsidiva ekhinokokkoza [Chemoprophylaxis of recurrence of echinococcosis]. Vestnik KGMA im. I.K. Akhunbaeva. 2014;4:162-4.
  45. Richter J. Anaphylactic shock ensuing therapeutic puncture of an echinococcal cyst. Parasitology Research. 2015;2:763-6.
  46. Chernousov AF. Maloinvazivnye vmeshatel’stva v lechenii tsistobiliarnykh svishchey posle ekhinokokkektomii iz pecheni [Minimally invasive interventions in the treatment of cystobiliary fistula after echinococcectomy of the liver]. Vestnik khirurgicheskoy gastroenterologii. 2011;2:36-41.
  47. Vishnevskiy VA, Efanov MG. Ekhinokokkoz pecheni. Khirurgicheskoe lechenie [Echinococcosis of the liver. Surgical treatment]. Dokazatel’naya gastroenterologiya. 2013;2:18-25.
  48. Nishanov FN. Maloinvazivnye metody khirurgicheskoy korrektsii oslozhnyonnoy ostatochnoy polosti posle ekhinokokkektomii pecheni [Minimally invasive methods of surgical correction of a complicated residual cavity after echinococcectomy of the liver]. Vestnik natsional’nogo mediko-khirurgicheskogo tsentra im. N.I. Pirogova. 2013;3(8):66-9.
  49. Vetshev PS, Musaev GKh, Bruslik SV. Ekhinokokkoz: sovremennoe sostoyanie problemy [Echinococcosis: current state of the problem]. Ukrainskiy zhurnal khirurgii. 2013;22(3):196-201.
  50. Prudkov MI, Amonov ShSh, Orlov OG. Operatsii iz mini-dostupa v khirurgicheskom lechenii ekhinokokkoza pecheni [Operations from the mini-access in the surgical treatment of liver echinococcosis]. Annaly khirurgicheskoy gepatologii. 2011;16(4):40-5.
  51. Tretyakov AA. Zakrytie ostatochnykh polostey pecheni [The closure of the residual cavities of the liver]. Vestnik khirurgii im. I.I. Grekova. 2012;171(6):97-9.
  52. Kalmykov EL, Gulov MK, Kapustin BB, Mukhabbatov DK, Nematzoda O, Zardakov SM, i dr. K voprosu o mini-invazivnoy khirurgii echinokokkoza pecheni [To the question about mini-invasive surgery of liver echinococcosis]. Novosti khirurgii. 2019;27(5):563-73.

Authors' information:

Amonov Shukhrat Shodievich
Doctor of Medical Sciences, Surgeon of the Department of Endoscopic Surgery, Republican Scientific Center for Cardiovascular Surgery; Assistant, Department of Surgical Diseases № 2, Avicenna Tajik State Medical University
ORCID ID: 0000-0002-3702-6584

Rakhmonov Dzhamakhon Akhmadovich
Candidate of Medical Sciences, Director of the Republican Scientific Center for Cardiovascular Surgery; Assistant, Department of Surgical Diseases № 2, Avicenna Tajik State Medical University
ORCID ID: 0000-0002-4427-0155

Fayziev Zokirdzhon Sharipovich
Candidate of Medical Sciences, Surgeon of the Department of Endoscopic Surgery, Republican Scientific Center for Cardiovascular Surgery
ORCID ID: 0000-0003-4172-4286

Bokiev Fatkhullo Bakhshulloevich
Candidate of Medical Sciences, Head of the Department of Endoscopic Surgery, Republican Scientific Center for Cardiovascular Surgery
ORCID ID: 0000-0003-2807-2324

Turakulov Farrukh Abduraufovich
Candidate of Medical Sciences, Surgeon of the Department of Endoscopic Surgery, Republican Scientific Center for Cardiovascular Surgery
ORCID ID: 0000-0002-1247-5068

Sangov Dilshod Safarovich
Candidate of Medical Sciences, Surgeon of the Department of Endoscopic Surgery, Republican Scientific Center for Cardiovascular Surgery
ORCID ID 0000-0001-6148-5126

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment.

Conflicts of interest: No conflict

Address for correspondence:

Amonov Shukhrat Shodievich
Doctor of Medical Sciences, Surgeon of the Department of Endoscopic Surgery, Republican Scientific Center for Cardiovascular Surgery; Assistant, Department of Surgical Diseases № 2, Avicenna Tajik State Medical University

734003, Republic of Tajikistan, Dushanbe, 33 Sanoi Street

Tel.: +992 (918) 761013

E-mail: shuhrat.amonov@yandex.ru

◄ Back to the list