Literature Reviews

doi: 10.25005/2074-0581-2019-21-2-291-297
SOFT TISSUE SARCOMA: A MODERN VIEW TO THE PROBLEM

V.V. Benberin1, B.T. Bayzakov2, N.A. Shanazarov1, S.V. Zinchenko3

1Medical center Hospital of President’s Affairs Administration of the Republic of Kazakhstan, Nur Sultan, Republic of Kazakhstan
2Medical Center of the West Kazakhstan Marat Ospanov Medical University, Aktobe, Republic of Kazakhstan
3Department of Surgery, Institute of Fundamental Medicine and Biology, Kazan (Volga region) Federal University, Kazan, Russian Federation

The review discusses the distribution and treatment of soft tissue sarcoma. Thus, about 10,000 new patients are registered in the Russian Federation every year; the incidence is 30 cases per 1 million populations. The age range of soft tissue sarcoma is on average 56-65 years with a peak in the age of 80-90 years. Fundamental aspects of the issue are illuminated. Thus, there are more than 100 histological types of soft tissue sarcoma; the most common include undifferentiated sarcomas, liposarcomas, leiosarcomas, synovial sarcomas and malignant tumor of peripheral nerve membranes. Considered issues of diagnostic criteria. According to the recommendations of the WHO to improve the accuracy of diagnosis in soft tissue sarcoma, the traditional histopathological examination should be supplemented with immunohistochemical and molecular methods. Studied modern approaches to the treatment of malignancies. One such approach is «Oncology Control», which means minimizing the risk of recurrence at the local and systemic level.

Keywords: Sarcoma, soft tissue sarcoma , diagnostic criteria of sarcoma, soft tissue sarcoma treatment standards, , soft tissue sarcoma classification.

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Authors' information:


Benberin Valeriy Vasilievich
, Corresponding Member of the National Academy of Sciences of the Republic of Kazakhstan, Doctor of Medical Sciences, Full Professor, Director of the Medical center Hospital of President’s Affairs Administration of the Republic of Kazakhstan

Bayzakov Beybit Tlektesovich
, Head of Radiation Therapy Department, Medical Center of the West Kazakhstan Marat Ospanov Medical University

Shanazarov Nasrulla Abdullaevich
, Doctor of Medical Sciences, Full Professor, Deputy Director of Science and Strategy Development, Medical center Hospital of President’s Affairs Administration of the Republic of Kazakhstan

Zinchenko Sergey Viktorovich
, Doctor of Medical Sciences, Head of the Department of Surgery, Institute of Fundamental Medicine and Biology, Kazan (Volga region) Federal University

Conflicts of interest: No conflict

Address for correspondence:


Shanazarov Nasrulla Abdullaevich
Doctor of Medical Sciences, Full Professor, Deputy Director of Science and Strategy Development, Medical center Hospital of President’s Affairs Administration of the Republic of Kazakhstan

010000, Republic of Kazakhstan, Nur Sultan, E495 Str., 2

Tel.: +7 (717) 2708081

E-mail: nasrulla@inbox.ru