Pathophysiology
doi: 10.25005/2074-0581-2018-20-2-3-218-223
PRELIMINARY RESULTS OF THE FAMILY-DOT PROGRAM FOR PEDIATRIC PATIENTS WITH DRUG-RESISTANT TUBERCULOSIS IN THE REPUBLIC OF TAJIKISTAN

H. Zander1, A. Springer1, D. Klyeschikova1, S. Dietrich2, B. Sharipov3, S. Ismoilov4

1Médecins Sans Frontières (MSF), Dushanbe, Republic of Tajikistan
2Médecins Sans Frontières (MSF), Berlin, Germany
3Republican Center for the Protection of the Population from Tuberculosis, Dushanbe, Republic of Tajikistan
4Dushanbe City Pediatric Tuberculosis Hospital, Dushanbe, Republic of Tajikistan

Objective: A description of the protocol of organizational peculiarities of cohort composition and preliminary results of the using the model of TB treatment program under the control of responsible family member Family-DOT (F-DOT) for pediatric patients with drug-resistant (DR) forms of TB (DR-TB) in the Republic of Tajikistan.

Methods: A descriptive analysis of existing MSF program data collected on eleven F-DOT patients between April 2017 and May 2018 is used.

Results: Eleven eligible patients with a stable form of tuberculosis provided the F-DOT program after receiving their prior consent. At this moment, seven of them are continuing therapy, while four of them have successfully completed the treatment. Among the participants of the program are children aged 1 to 17 years old, 54.5% of girls and 54.5% of patients with extensively drug-resistant tuberculosis (XDR TB).

Conclusion: Earlier empirical data and initial results show that there the possibility and viability is the use of models of therapy and home care for pediatric patients with DR-TB in the Republic of Tajikistan.

Keywords: Drug-resistant forms of tuberculosis, MDR-TB, XDR-TB, approaches to the therapy of children, new methods of management of tuberculosis patients, Family-DOT (F-DOT) program.

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Authors' information:

Heike Zander, Employee of the International Organization "Médecins Sans Frontières" (Tajikistan)

Adel Springer, Employee of the International Organization "Médecins Sans Frontières" (Tajikistan)

Jarmila Klyeschikova, Medical Coordinator of the International Organization "Médecins Sans Frontières" (Tajikistan)

Sebastian Dietrich, Member of the International Organization "Médecins Sans Frontières" (Germany)

Bobodzhon Sharipov, Deputy Director of the Republican Center for the Protection of the Population from Tuberculosis

Safarali Ismoilov, Phthisiatrician, Dushanbe City Pediatric Tuberculosis Hospital

Conflicts of interest: No conflict

Address for correspondence:

Jarmila Klyeschikova

Medical Coordinator of the International Organization "Médecins Sans Frontières" (Tajikistan)

734025, Republic of Tajikistan, Dushanbe, Bukhoro str., 5/3

Tel.: (+992) 985 868080

E-mail: tajikistan-medco@oca.msf-oca

Materials on the topic:
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  5. IN VIVO STUDY OF WOUND-HEALING ACTIVITY OF POLYSACCHARIDE GEL WITH ENCAPSULATED SEA-BUCKTHORN OIL (HIPPOPHAE RHAMNOIDES)
  6. DYNAMICS OF DRUG RESISTANCE IN M. TUBERCULOSIS DURING THE NEW CORONAVIRUS INFECTION PANDEMIC IN DUSHANBE: THE NEED FOR URGENT MEASURES
  7. IMPLEMENTATION STUDY IN PREVENTION AND CONTROL OF DRUG-RESISTANT TUBERCULOSIS DURING THE COVID-19 PANDEMIC IN DUSHANBE
  8. PREVALENCE OF MYCOBACTERIUM TUBERCULOSIS AMONG CHILDREN AT THE RESERVOIRS OF INFECTION IN THE REPUBLIC OF TAJIKISTAN
  9. ANTITUBERCULOSIS DRUG ALLERGY IN PATIENTS WITH MULTIDRUG-RESISTANT TUBERCULOSIS
  10. STIGMA AND DISCRIMINATION ASSOCIATED WITH TUBERCULOSIS

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