Pathophysiology
doi: 10.25005/2074-0581-2018-20-2-3-198-201
PECULIARITIES OF THE CLINICAL COURSE OF THE MULTI-DRUG RESISTANT FORM OF TUBERCULOUS SPONDYLITIS IN THE KYRGYZ REPUBLIC

M.D. Abdiev, M.K. Kubatbekov, D.A. Kushubakov, О.R. Botobekov, E.A. Baynazarov

Department of Bones and Joints Tuberculosis Surgery, National Center for Phthisiology, Bishkek, Kyrgyz Republic

Objective: To study the clinical course of multiple drug resistance in patients with tuberculous spondylitis in the Kyrgyz Republic.

Methods: Analyzed 877 medical histories of patients with tuberculous spondylitis of the cervical, thoracic, lumbar and lumbosacral spine, which was on treatment in the Department of Bones and Joints Tuberculosis Surgery from 2013 to 2017.

Results: It is established that 715 patients (81.5%) had a sensitive form of tuberculous spondylitis; 153 (17.4%) is primarily resistant and 9 (0.8%) is a secondarily resistant form. In the group of patients in the sensitive form of tuberculosis men were 370, women 345, and among the patients with the resistant form of tuberculous spondylitis of men and women were 86 and 76 people respectively.

Conclusion: Over the period of 2013-2017 y., the Kyrgyz Republic marked the growth in multi-drug resistant forms of tuberculous spondylitis with the rapid development of formidable neurological complications, such as meningitis, paresis, paraparesis, paralysis, and dysfunctions of pelvic organs.

Keywords: Multiple drug resistance, spinal tuberculosis, bacteriological study of the pathological material.

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Authors' information:

Abdiev Marat Dzhumadylovich,
Candidate of Medical Sciences, Deputy Director for Science of the National Center for Phthisiology

Kubatbekov Munarbek Kubatbekovich,
Head of the Department of Bones and Joints Tuberculosis Surgery, National Center for Phthisiology

Kushubakov Danil Amankulovich,
Phthisiatrician of the Department of Bones and Joints Tuberculosis Surgery, National Center for Phthisiology

Baynazarov Elchibek Abdulakhatovich,
Researcher, Department of Bones and Joints Tuberculosis Surgery, National Center for Phthisiology

Botobekov Oskon Rakhmatzhanovich,
Researcher, Department of Bones and Joints Tuberculosis Surgery, National Center for Phthisiology

Conflicts of interest: No conflict

Address for correspondence:

Abdiev Marat Dzhumadylovich

Candidate of Medical Sciences, Deputy Director for Science of the National Center for Phthisiology

720020, Kyrgyz Republic, Bishkek, Akhunbaev str., 90a

Tel.: (+996) 312 570925

E-mail: marat.abdievtbc@gmail.com

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