Literature Reviews
doi: 10.25005/2074-0581-2019-21-2-298-304
MODERN MEASURES OF ANTI-TB INFECTION CONTROL

O.I. Bobokhodzhaev1, Z.T. Avgonov2, S.S. Sattorov2

1Department of Physiopulmonology, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
2Department of Science, Scientific Research Institute of Preventive Medicine of Tajikistan, Dushanbe, Republic of Tajikistan

For effective implementation of modern TB eradication measures should be available to data on TB transmission factors and epidemiology based on it pathogenesis, from infection before the outcome of its current. Review article reveals the modern requirements and methods of organizing anti-TB infection control. The results of the publications, their interpretation and comparison with the situation in Tajikistan are presented. The importance of following infection control measures at home, including the isolation of bacterioexcretion persons, timely verification of mycobacterium TB infection, vaccination and chemoprophylaxis to improve the TB epidemiological situation. It is noted that the evidence-based principles of preventing nosocomial transmission of TB infection have reduced the number of hospitalizations and minimized the duration of patients’ stay in TB hospitals, while increasing the cohorts of patients who are initially on outpatient chemotherapy. The review presented and the real level of anti-TB infection control in the Republic of Tajikistan, especially in the nidus of infection and among contact persons, indicates the urgent need to rethink approaches to preventing transmission of this disease.

Keywords: Tuberculosis, infection control, disinfection , mycobacteria tuberculosis, immuno-diagnostic methods, prevention.

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References
  1. Alekseenko SN, Drobot EV. Profilaktika zabolevaniy. Tuberkulyoz: epidemiologiya, faktory riska, profilaktika [Disease prevention. Tuberculosis: epidemiology, risk factors, prevention]. Moscow, RF: “Rossiyskaya Akademiya estestvoznaniya”; 2015. 449 p.
  2. Aksyonova VA, Klevno NI, Kavtarashvili SM, Kazakov AV, Pakhlavonova AD. Ochag tuberkulyoznoy infektsii kak risk razvitiya u detey tuberkulyoza s mnozhestvennoy lekarstvennoy ustoychivost’yu [Outbreak of tuberculosis infection as a risk of developing multidrug-resistant tuberculosis in children]. Tuberkulyoz i bolezni lyogkikh. 2018;96(1):11-7.
  3. Pokrovskiy VI, Briko NI. (red.) Obshchaya epidemiologiya s osnovami dokazatel’noy meditsiny [General epidemiology with the basics of evidencebased medicine]. Vtoroe izdanie. Moscow, RF: GEOTAR-Media; 2012. 494 p.
  4. Dara M. TB in Central Asia. WHO Regional Office for Europe. Panorama: Public Health. 2016;2(1):10-4
  5. Dharmadhikari AS, Mphahlele M, Venter K, Stoltz A, Mathebula R, Masotla T. et al. Rapid impact of effective treatment on transmission of multidrugresistant tuberculosis. Int J Tuberc Lung Dis. 2014;18(9):1019-25.
  6. Oshchepkova NM, Vinokurova MK. Osobennosti ochagov tuberkulyoza v sel’skoy mestnosti v usloviyakh regiona Kraynego Severa [Features foci of tuberculosis in rural areas in the conditions of the Far North region]. Yakutskiy meditsinskiy zhurnal. 2013;1(41):85-7.
  7. Vinokurova MK, Aleksandrov VL, Yakovleva LP, Oshchepkova NM. Tendentsii razvitiya epidemiologicheskoy situatsii po tuberkulyozu v Respublike Sakha (Yakutiya) v 2004-2011 gg. [Trends in the epidemiological situation of tuberculosis in the Republic of Sakha (Yakutia) in 2004-2011]. Yakutskiy meditsinskiy zhurnal. 2013;1(41):58-62.
  8. Aliev SP, Bobokhodzhaev OI, Makhmudzoda IS, Mirzoeva FO, Ukumatshoeva LSh, Mirzoeva SR. Effektivnost’ vyyavleniya sluchaev tuberkulyoza sredi naseleniya g. Dushanbe Respubliki Tadzhikistan [Efficacy of tuberculosis cases detection among the population of Dushanbe in the Republic of Tajikistan]. Vestnik Avitsenny [Avicenna Bulletin]. 2018;20(4):427-30. Available from: http://dx.doi.org/10.25005/2074-0581-2018-20-4-427-430.
  9. Sirodzhidinova UYu, Bobokhodzhaev OI, Pirov KI. Vyyavlyaemost’ lokal’nogo tuberkulyoza u shkol’nikov v raznykh regionakh Respubliki Tadzhikistan [Detectability of pulmonary tuberculosis in schoolchildren from different regions of the Republic of Tajikistan]. Vestnik Avitsenny [Avicenna Bulletin]. 2017;19(1):90-3. Available from: http://dx.doi.org/10.25005/2074-0581- 2017-19-1-90-93.
  10. Shilova MV. Sovershenstvovanie dispansernogo nablyudeniya kontingentov protivotuberkulyoznykh uchrezhdeniy na osnove personal’nogo monitoringa patsientov s primeneniem komp’yuternykh tekhnologiy [Improvement of follow-up monitoring of contingents of tuberculosis institutions based on personal patient monitoring using computer technologies]. Tuberkulyoz i bolezni lyogkikh. 2014;7:8-15.
  11. Mordyk AV, Turina AA, Kondrya AV, Aroyan AR, Tsygankova EA. Vyyavlenie razlichnykh form i lokalizatsiy tuberkulyoza u detey raznogo vozrasta: rol’ skriningovogo obsledovaniya [Identification of various forms and localizations of tuberculosis in children of different ages: the role of screening tests]. Rossiyskiy pediatricheskiy zhurnal. 2016;19(3):151-6.
  12. Barmina NA, Baryshnikova LA, Shurygin AA, Reykhardt VV. Skrining latentnoy tuberkulyoznoy infektsii s primeneniem allergena tuberkulyoznogo rekombinantnogo [Screening for latent tuberculosis infection using a recombinant tuberculosis allergen]. Tuberkulyoz i bolezni lyogkikh. 2016;94(5):56-60.
  13. Slogotskaya LV, Bogorodskaya EM. Sravnitel’naya kharakteristika immunologicheskikh testov dlya vyyavleniya tuberkulyoznoy infektsii. Vozmozhnost’ massovogo skrininga [Comparative characteristics of immunological tests for the detection of tuberculosis infection]. Tuberkulyoz i bolezni lyogkikh. 2016;94(5):5-17.
  14. Kislichkin NN, Furs SM, Krasilnikov NV. Diagnostika tuberkulyoza. Tuberkulin ili diaskintest – chto vybrat’? [Diagnosis of tuberculosis. Tuberculin or diaskintest – what to choose?]. Epidemiologiya i infektsionnye bolezni. 2014;5:50-5.
  15. Poddubnaya LI, Shilova EP, Stepchenko IM. Epidemiologicheskie faktory i immunnye proby v formirovanii grupp riska po zabolevaniyu tuberkulyozom [Epidemiological factors and immune tests in the formation of risk groups for the disease of tuberculosis]. Tuberkulyoz. 2015;5:153-4.
  16. Vozyakova TR, Masterova AV, Elenkina ZhV, Kudlay DA. Kompleksnaya otsenka diagnosticheskikh metodov vyyavleniya tuberkulyoznoy infektsii u detey i podrostkov v Chuvashskoy Respublike [Comprehensive assessment of diagnostic methods for detecting tuberculosis infection in children and adolescents in the Chuvash Republic]. Rossiyskiy vestnik perinatologii i pediatrii. 2017;62(4):105-12.
  17. Aksyonova VA, Baryshnikova LA, Klevno NI. Novye vozmozhnosti skrininga i diagnostiki razlichnykh proyavleniy tuberkulyoznoy infektsii u detey i podrostkov v Rossii. V: Paltsev VA. (red) Kozhnaya proba s preparatom «Diaskintest» – novye vozmozhnosti identifikatsii tuberkulyoznoy infektsii. Izd. 2-e. [New possibilities of screening and diagnosing various manifestations of tuberculosis infection in children and adolescents in Russia. In: Paltsev VA (ed.) Skin test with «Diaskintest» – a new possibilities of tuberculosis infection identification. 2nd ed.]. Moscow, RF: ;2011. p. 134-52.
  18. Ovsyankina ES, Gubkina MF, Panova LV, Yukhimenko NV. K voprosu o vliyanii metoda skrininga tuberkulyoznoy infektsii u detey i podrostkov na formirovanie grupp riska i diagnostiku zabolevaniya [To the question of the influence of screening methods of tuberculosis infection in children and adolescents on the formation of risk groups and the diagnosis of the disease]. Pediatricheskaya farmakologiya. 2016;13(6):617.
  19. Slogotskaya L, Bogorodskaya EM, Senchikhina OYu, Nikitina GV, Kudlay DA. Formirovanie grupp riska zabolevaniya tuberkulyozom pri razlichnykh immunologicheskikh metodakh obsledovaniya detskogo naseleniya [Formation of groups at risk of tuberculosis in various immunological methods of examination of the child population]. Rossiyskiy pediatricheskiy zhurnal. 2017;20(4):204-13.
  20. Poddubnaya LV, Shilova EP, Stepchenko IM, Kononenko VG. Epidemiologicheskie faktory i immunologicheskie proby v formirovanii grupp riska po zabolevaniyu tuberkulyozom [Epidemiological factors and immunological tests in the formation of risk groups for the disease of tuberculosis]. Tuberkulyoz i bolezni lyogkikh. 2015;5:153-4.
  21. Aggerbeck H, Giemza R, Joshi P. Randomised Clinical trial investigating the specificity of a Novel skin test (C-TB) for diagnosis of M. Tuberculosis infection. PloS ONE. 2013;8(5):e64215.
  22. Legesse M, Ameni G, Mamo G. Community-based cross-sectional survey of latent tuberculosis infection in Afar Pastoralists, Ethiopia, using QuantiFERON-TB Gold In-Tube and tuberculin skin test. BMC Infect Dis.2011;11:89.
  23. Pollock N, Mc Adam A, Pai M. Interferon gamma-realease assays for diagnosis of latent tuberculosis in healthcare workers in low-incidence settings: pros and cons. Clin Chem.2014;60(5):714-8.
  24. Rangaka M, Wilkinson K, Glynn J. Predictive value of interferon-gamma realease assays for incident active tuberculosis: systematic rewiew and metaanalysis. Lancet Infect Dis.2012;12:45-55.
  25. Diel R, Loddenkemper R, Nienhaus A. Evidence-based comparison of commercial interferon gamma release assay for detecting active TB: a metaanalysis. Chest. 2010;137(4):952-68.
  26. Machingaidze S, Verver S, Mulenga H. Predictive value of recent QuantiFERON conversion for tuberculosis diseases in adolescents. Am J Respir Crit Care Med. 2012;186(10):1051-6.
  27. Lalvani A, Pareek MA. A 100 year update on diagnosis of tuberculosis infection. Br Med Bull. 2010;93(1):69-84.
  28. Bakir M, Dosanjh DPS, Deeks JJ, Soysal A, Millington KA, Efe S, et al. Use of T cell-based diagnosis of tuberculosis infection to optimize interpretation of tuberculin skin testing for child tuberculosis contacts. Clin Infect Dis. 2009;48(3):302-12
  29. Gandhi NR, Weissman D, Moodley P, Ramathai M, Elson I, Kreiswirth BN, et al. Nosocomial transmission of extensively drug-resistant tuberculosis in a rural hospital in South Africa. J Infect Dis. 2013;207(1):9-17.
  30. Bantubani N, Kabera G, Connolly C, Rustomjee R, Reddy T, Cohen T, et al. High rate of potentially infectious tuberculosis and multidrugresistant tuberculosis (MDR-TB) among hospital inpatients in KwaZulu Natal, South Africa indicate risk of nosocomial transmission. PloS ONE. 2014;9(3):e90868.
  31. Shenoi SV, Escombe AR, Friedland G. Transmission of drug-susceptible and drug-resistant tuberculosis and the critical importance of airborne infection control in the era of HIV infection and highly active antiretroviral therapy roolouts. Clin Infect Dis. 2010;50(Suppl.3):231-7.
  32. Starodubov VI, Shchepin OP. (red.) Obshchestvennoe zdorov’ye i zdravookhranenie [Public health and health care]. Moscow, RF: GEOTARMedia; 2014. 624 p.
  33. Perelman MI, Bogadelnikova IV. Ftiziatriya [Phthisiology]. Moscow, RF: GEOTAR-Media; 2010. 445 p.
  34. Shuvalova EP. Infektsionnye bolezni [Infectious diseases]. Moscow, RF: SpetsLit; 2014. 725 p.
  35. Dyachkova SYa, Andreeva VV, Kinshina MM, Korablyova TP. (red.) Metodicheskie rekomendatsii dlya spetsialistov, uchastvuyushchikh v organizatsii zdorov’esberezheniya v obrazovatel’nykh uchrezhdeniyakh i v skriningovykh osmotrakh doshkol’nikov, uchashchikhsya i studentov [Guidelines for professionals involved in the organization of health preservation in educational institutions and screening examinations of preschoolers, pupils and students]. Voronezh, RF: Voronezhskiy gosudarstvennyy universitet; 2011. 326 p.
  36. Pokrovskiy VI, Akimkin VG, Briko NI, Brusina NI, Zueva LP, Kovalishena OV, i dr. Natsional’naya kontseptsiya profilaktiki infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi, i informatsionnyy material po eyo polozheniyam [The national concept of prevention of infections associated with the provision of medical care, and information material on its provisions]. Nizhniy Novgorod, RF: Remedium Privolzh’e; 2012. 84 p.
  37. Kuzin VV, Shmatkova EB, Grishchenko NS, Rudnitskaya TI, Fursov MV, Potapov VD. Eksperimental’noe sravnenie aerozol’nogo metoda pri dezinfektsii vozdukha i poverkhnostey, kontaminirovannykh M. tuberculosis [Experimental comparison of the aerosol method for disinfecting air and surfaces contaminated with M. tuberculosis]. Tuberkulyoz i bolezni lyogkikh. 2018;96(1):35-40.

Authors' information:

Bobokhodzhaev Oktam Ikramovich
, Doctor of Medical Sciences, Professor of the Department of Physiopulmonology, Avicenna Tajik State Medical University ORCID ID 0000-0002-8619-3426

Avgonov Ziyovudin Tulforovich
,Applicant of Scientific Research Institute of Preventive Medicine of Tajikistan ORCID ID 0000-0002-6786-7966

Sattorov Safar Saydamirovich
, Applicant of Scientific Research Institute of Preventive Medicine of Tajikistan ORCID ID 0000-0001-9620-9551

Conflicts of interest: No conflict

Address for correspondence:

Bobokhodzhaev Oktam Ikramovich
Doctor of Medical Sciences, Professor of the Department of Physiopulmonology, Avicenna Tajik State Medical University

734003, Republic of Tajikistan, Dushanbe, Rudaki Ave., 139

Tel.: +992 (985) 868080

E-mail: bobokhojaev@mail.ru

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