N.M. Khmelnitskaya, Z.Yu. Melieva, V.A. Lipova, F.Yu. Melieva
COMPARATIVE MORPHOLOGICAL CHARACTERISTIC OF POORLY DIFFERENTIATED SEROUS AND ENDOMETRIOID OVARIAN CARCINOMAS
Department of Pathological Anatomy, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia
Objective: Detection of the morphological symptoms for differential diagnostic of the serous and endometrioid ovarian carcinomas with a low degree of differentiation.
Methods: The results of morphological diagnostics of 100 patients of different age groups suffering from ovarian cancer were analyzed.
Results: Determination of specific histological and cellular features of cancer cells, helping to distinguish poorly differentiated serous carcinoma from endometrioid ovarian cancer with reduced differentiation.
Conclusions: The carried out studies allows to establish a histogenetic morphological diagnosis on the basis of the analysis of the operating material, rationally drawing up a plan for treating the patient and determining the prognosis of the disease. It is necessary to carry out a macro- and microscopic examination of the operating material using the traditional methods of staining, as well as with the use of immunohistochemistry.
Keywords: Poorly differentiated ovarian carcinomas, clinical stages of tumour spread, morphology, immunohistochemistry
Khmelnitskaya Natalia Mikhaylovna, Doctor of Medical Sciences, Professor of the Department of Pathological Anatomy, NWSMU named after I.I. Mechnikov
Melieva Zukhra Yusufdzhanovna, Assistant of the Department of Pathological Anatomy of the NWSMU named after I.I. Mechnikov
Lipova Valentina Aleksandrovna, Candidate of Biological Sciences, Associate Professor of the Department of Pathological Anatomy, NWSMU named after I.I. Mechnikov
Melieva Fotima Yusufdzhanovna, Candidate of Medical Sciences, Assistant of the Department of Pathological Anatomy, NWSMU named after I.I. Mechnikov
Address for correspondence
Melieva Zukhra Yusufdzhanovna
Assistant of the Department of Pathological Anatomy
NWSMU after I.I. Mechnikov
191015 Russian Federation, Saint-Petersburg, Kirochnaya Str. 41
Tel: (+7) 812 303 5000 (ext. 8323); (+7) 952 237 3120