Oncology

doi: 10.25005/2074-0581-2018-20-2-3-157-165
CHANGE OF EPIDEMIOLOGICAL SITUATION OF COLORECTAL CANCER IN KAZAKHSTAN AFTER INTRODUCTION OF SCREENING

D.R. Kaydarova1, A.Zh. Zhylkaydarova1, A.A. Akhetov2, N.A. Shanazarov2, K.U. Batyrbekov3

1Kazakh Scientific Research Institute of Oncology and Radiology, Almaty, Republic of Kazakhstan
2Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, Astana, Republic of Kazakhstan
3Scientific Research Institute of Traumatology and Orthopedics, Astana, Republic of Kazakhstan

Objective: To assess the change in the epidemiological situation of colorectal cancer (CRC) in Kazakhstan after the introduction of screening.

Methods: Retrospectively, according to regional reports on endoscopic screening conducted an analysis general morbidity of CRC in the regions of the Republic of Kazakhstan.

Results: The highest incidence of CRC in Kazakhstan was registered in Pavlodar (14.5%), North Kazakhstan (14.1%), Almaty (12.1%), Kostanay (11.5%), East Kazakhstan (11.0%), Karaganda (10.7%), Akmola (10.1%) regions and Astana City (8.8%). The average indicator for the Kazakhstan as a whole was 11.6%. Our data confirmed the fact that CRC is more often registered among males. In the analysis of the age-specific incidence of CRC, it is revealed the increase with age this peak morbidity falls on the age category over 70 years. Unit weight indicators of I-II, III and IV stages of newly identified cases of CRC for 2004-2014 clearly shows an increase in the specific weight of the I-II stage by almost 2 times (from 35% to 67.4%) by reducing for the specified period of specific weight of IV stages from 19.3% to 13.1% and stage III more than 2 times (from 45.7% to 19.5%).

Conclusions: The analysis of the prevalence of CRC, both in the regions and in the Republic of Kazakhstan as a whole, has shown an increase of morbidity rates of given pathology. The stage-by-stage prevalence of morbidity shows its increase due to the I and II stages from 2011 when the population screening of CRC was introduced. This allows to speak about the positive economic effect of screening since the treatment of I and II stages of CRC requires significantly less funds.

Keywords: Endoscopic screening, colonoscopy, colorectal cancer, epidemiological situation.

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Authors informations:

Kaydarova Dilyara Radikovna, Doctor of Medical Sciences, Academician of the National Academy of Sciences of Kazakhstan, Director of the Kazakh Scientific Research Institute of Oncology and Radiology

Zhylkaydarova Alma Zhalelovna, Candidate of Medical Sciences, Head of the Specialized Consultative and Diagnostic Department, Kazakh Scientific Research Institute of Oncology and Radiology

Akhetov Amir Amantaevich, Doctor of Medical Sciences, Director, Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan

Shanazarov Nasrulla Abdullaevich, Doctor of Medical Sciences, Full Professor, Deputy Director for Science, Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan

Batyrbekov Kanat Umirzakovich, Endoscopist, Scientific Research Institute of Traumatology and Orthopedics

Address for correspondence:

Batyrbekov Kanat Umirzakovich

Endoscopist, Scientific Research Institute of Traumatology and Orthopedics

010000, Republic of Kazakhstan, Astana, Abylaykhan Ave., 15а

Tel.: (+7) 707 4744980

E-mail: dr.kanat77@mail.ru

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