Cardiology

doi: 10.25005/2074-0581-2018-20-1-37-41
INFLUENCE OF THE MAIN LEFT CORONARY ARTERY DISEASE ON THE LEFT VENTRICULAR CONTRACTILE FUNCTION IN THE LONG TERM PERIOD

N.M. Kuzmina

Department of Hospital Therapy with Courses of Cardiology and Functional Diagnostics, Izhevsk State Medical Academy, Izhevsk, Russian Federation

Objective: To study the dynamics of the left ventricular ejection fraction (LVEF) in the long-term period in patients after emergency percutaneous coronary intervention (PCI).

Methods: Retrospectively studied the 155 medical histories of patients with the acute coronary syndrome, who underwent PCI. In two years later, 95 patients from the initial sample conducted 2D echocardiography on an apparatus of expert class "Vivid 7".

Results: LVEF in the sample 2 years after PCI was significantly increased (56.7447±6.7233% and 58.2021±6.3544%, t=3.0499, p=0.0031). A direct statistically significant relationship was found between such parameters as: symptom-onset-to-balloon (SOTB) time and LVEF (r=0.3, p<0.05); SOTB and the number of dysfunctional LV regions (r=0.18, p<0.05); the body mass index and left main lesion (r=0.24, p<0.05) and the inverse statistically significant relationship between the left main lesion and the LVEF (r =-0.16, p<0.05 ). It is established that for left main stenosis more than 50%, the risk of a reducing in the LVEF is increased in four times.

Conclusions: In case of hemodynamically significant stenosis of the left main, timely revascularization should be performed to improve the quality of life and increase the lifespan. This allows improving the contractile function of the LV and reducing the risk of developing severe chronic heart failure.

Keywords: Acute coronary syndrome, myocardial infarction, unstable angina, main left coronary artery, relative risk, ejection fraction.

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Authors informations:

Kuzmina Natalya Mikhaylovna, Full-time Postgraduate Student of the Department of Hospital Therapy with Courses of Cardiology and Functional Diagnostics, Izhevsk State Medical Academy

Address for correspondence:

Kuzmina Natalya Mikhaylovna
Full-time Postgraduate Student of the Department of Hospital Therapy with Courses of Cardiology and Functional Diagnostics, Izhevsk State Medical Academy

426034, Russian Federation, Udmurt Republic, Izhevsk, str. Kommunarov, 281, Department 28

Tel.: (+7) 912 4525643

E-mail: natalyes89@mail.ru

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